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Abcc5
Gene Detail
 Symbol
Name
ID
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
MGI:1351644
Synonyms 2900011L11Rik, Abcc5a, Abcc5b, Mrp5
Feature Type protein coding gene
Genetic Map
Chromosome 16
12.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:20331303-20426394 bp, - strand
From VEGA annotation of GRCm38

  95092 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21164  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Abcc5

Human
homologs
Human Homolog ABCC5, ATP-binding cassette, sub-family C (CFTR/MRP), member 5
NCBI Gene ID 10057
neXtProt AC  NX_O15440
Human Synonyms  ABC33, EST277145, MOATC, MOAT-C, MRP5, pABC11, SMRP
Human Chr (Location)  3q27; chr3:183919934-184017939 (-)  GRCh38
Alleles
and
phenotypes
All alleles(81) : Gene trapped(77) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele display normal cGMP transport into erythrocyte membrane vesicles.
 
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process transmembrane transport, transport
Component integral component of membrane, membrane, ...
Function ATPase activity, ATPase activity, coupled to transmembrane movement of substances, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (210)    Tissues (106)    Images (36)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 210
cDNA source data(120)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(124) cDNA(124)
Microarray probesets(11)
Other database
links
VEGA Gene ModelOTTMUSG00000025954 (Evidence)
Ensembl Gene ModelENSMUSG00000022822 (Evidence)
Entrez Gene27416 (Evidence)
UniGene20845
DFCITC1575353, TC1585981, TC1609945, TC1623079, TC1762666
DoTSDT.101391987, DT.101403208, DT.110729893, DT.525053, DT.91377552, DT.94285319, DT.97368185, DT.99841262
NIA Mouse Gene IndexU036884
Consensus CDS ProjectCCDS28045.1, CCDS28046.1
International Mouse Knockout Project StatusAbcc5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025954 VEGA Gene Model | MGI Sequence Detail 95092 C57BL/6J ±  kb
transcript OTTMUST00000064008 VEGA | MGI Sequence Detail 5811 Not Applicable 
polypeptide OTTMUSP00000031743 VEGA | MGI Sequence Detail 1436 Not Applicable 

For the selected sequences
All sequences(91) RefSeq(22) UniProt(5)
Polymorphisms SNPs within 2kb(849 from dbSNP Build 137)    SNPs within 2kb including multiple locations(861)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR017871 ABC transporter, conserved site
InterPro IPR003439 ABC transporter-like
InterPro IPR001140 ABC transporter, transmembrane domain
InterPro IPR011527 ABC transporter, transmembrane domain, type 1
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000003561 multidrug resistance-associated protein 5
References (Earliest) J:58835 Konig J, et al., Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim Biophys Acta. 1999 Dec 6;1461(2):377-94
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(42)
Other
accession IDs
MGI:1351643, MGI:1925590, MGI:2146379

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory