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Peg12 Gene Detail
Summary
  • Symbol
    Peg12
  • Name
    paternally expressed 12
  • Synonyms
    Frat3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351637
    NCBI Gene: 27412
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:62111619-62114258 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 34.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    127 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351637
 protein coding gene Chr7:62111619-62114258 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032329
 protein coding gene Chr7:63550437-63552941 (-)
A/J MGP_AJ_G0032308
 protein coding gene Chr7:62342634-62345270 (-)
AKR/J MGP_AKRJ_G0032244
 protein coding gene Chr7:63660996-63663618 (-)
BALB/cJ MGP_BALBcJ_G0032320
 protein coding gene Chr7:62025523-62028165 (-)
C3H/HeJ MGP_C3HHeJ_G0032033
 protein coding gene Chr7:64271231-64273862 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032813
 protein coding gene Chr7:66313305-66315945 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029820
 protein coding gene Chr7:65363800-65366443 (-)
CAST/EiJ MGP_CASTEiJ_G0031362
 protein coding gene Chr7:55048151-55050790 (-)
CBA/J MGP_CBAJ_G0031999
 protein coding gene Chr7:68443763-68448614 (-)
DBA/2J MGP_DBA2J_G0032155
 protein coding gene Chr7:61162745-61165363 (-)
FVB/NJ MGP_FVBNJ_G0032109
 protein coding gene Chr7:61210410-61213042 (-)
LP/J MGP_LPJ_G0032235
 protein coding gene Chr7:64746593-64749097 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032146
 protein coding gene Chr7:68686836-68689475 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032830
 protein coding gene Chr7:62928749-62931386 (-)
PWK/PhJ MGP_PWKPhJ_G0031082
 protein coding gene Chr7:54140588-54143262 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030923
 protein coding gene Chr7:50050056-50052687 (-)
WSB/EiJ MGP_WSBEiJ_G0031480
 protein coding gene Chr7:63304081-63306709 (-)



Homology
more
  • Human Ortholog
    FRAT1, FRAT regulator of Wnt signaling pathway 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FRAT1, FRAT regulator of Wnt signaling pathway 1
  • Links
    NCBI Gene ID: 10023
    UniProt: Q92837

  • Chr Location
    10q24.1; chr10:97319271-97321915 (+)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    12 phenotype references
Homozygous mice are healthy and fertile with no obvious abnormalities.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    780
  • Tissues
    51
  • cDNA Data
    6
  • Literature Summary
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27412 NCBI Gene Model | MGI Sequence Detail 2640 C57BL/6J ±  kb
transcript NM_013788 RefSeq | MGI Sequence Detail 2640 ZRU/MplStud  
polypeptide NP_038816 RefSeq | MGI Sequence Detail 283 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR008014 Glycogen synthase kinase-3 binding protein
Molecular
Reagents
less
  • All nucleic 12
    Genomic 1
    cDNA 6
    Primer pair 5

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Developmental Gene Expression 14
    Diseases 1
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:340777 Laddach A, et al., A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia. Nat Commun. 2023 Sep 22;14(1):5904
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/09/2026
MGI 6.24 		The Jackson Laboratory