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Pald1 Gene Detail
Summary
  • Symbol
    Pald1
  • Name
    phosphatase domain containing, paladin 1
  • Synonyms
    mKIAA1274, paladin, X99384
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351623
    NCBI Gene: 27355
Location & Maps
more
  • Sequence Map
    Chr10:61319657-61383523 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      63867 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 32.19 cM, cytoband B4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PALD1, phosphatase domain containing, paladin 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PALD1, phosphatase domain containing, paladin 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    KIAA1274, PALD
  • Links
    NCBI Gene ID: 27143
    neXtProt AC: NX_Q9ULE6

  • Chr Location
    10q22.1; chr10:70458545-70568450 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8453
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PALD1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    68
  • Chemically induced (other)
    1
  • Gene trapped
    64
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Pald1
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020092 Ensembl Gene Model | MGI Sequence Detail 63867 C57BL/6J ±  kb
transcript ENSMUST00000020289 Ensembl | MGI Sequence Detail 4274 Not Applicable  
polypeptide ENSMUSP00000020289 Ensembl | MGI Sequence Detail 859 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    382 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR003595 Protein-tyrosine phosphatase, catalytic
    IPR029021 Protein-tyrosine phosphatase-like
Molecular
Reagents
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  • All nucleic 63
    cDNA 63

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
  • Latest
    J:181634 Wallgard E, et al., Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development. Dev Dyn. 2012 Apr;241(4):770-86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory