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Mrpl2 Gene Detail
Summary
  • Symbol
    Mrpl2
  • Name
    mitochondrial ribosomal protein L2
  • Synonyms
    CGI-22, MRP-L14, Rpml14
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351622
    NCBI Gene: 27398
Location & Maps
more
  • Sequence Map
    Chr17:46646229-46650139 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3911 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 22.90 cM, cytoband C
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    MRPL2, mitochondrial ribosomal protein L2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MRPL2, mitochondrial ribosomal protein L2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-22, MRP-L14, RPML14
  • Links
    NCBI Gene ID: 51069
    neXtProt AC: NX_Q5T653

  • Chr Location
    6p21.3; chr6:43054029-43060186 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype reference
  • All Mutations and Alleles
    2
  • Targeted
    2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024284 VEGA Gene Model | MGI Sequence Detail 3911 C57BL/6J ±  kb
transcript OTTMUST00000059467 VEGA | MGI Sequence Detail 1031 Not Applicable  
polypeptide OTTMUSP00000028925 VEGA | MGI Sequence Detail 306 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    21 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010582 39S ribosomal protein L2, mitochondrial
  • InterPro Domains
    IPR012340 Nucleic acid-binding, OB-fold
    IPR002171 Ribosomal protein L2
    IPR005880 Ribosomal protein L2, bacterial/organellar-type
    IPR022669 Ribosomal protein L2, C-terminal
    IPR014722 Ribosomal protein L2 domain 2
    IPR014726 Ribosomal protein L2, domain 3
    IPR022666 Ribosomal Proteins L2, RNA binding domain
    IPR008991 Translation protein SH3-like domain
Molecular
Reagents
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  • All nucleic 99
    cDNA 99

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Gene Ontology 6
    Phenotypes 1
  • Earliest
    J:58917 O'Brien TW, et al., Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences. J Biol Chem. 1999 Dec 17;274(51):36043-51
  • Latest
    J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory