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Mrpl39 Gene Detail
Summary
  • Symbol
    Mrpl39
  • Name
    mitochondrial ribosomal protein L39
  • Synonyms
    MRP-L5, Rpml5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351620
    NCBI Gene: 27393
  • Gene Overview
    MyGene.info: MRPL39
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:84717576-84735742 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 46.92 cM, cytoband C3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    203 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351620
protein coding gene Chr16:84717576-84735775 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022967
protein coding gene Chr16:85293663-85312716 (-)
A/J MGP_AJ_G0022935
protein coding gene Chr16:81408372-81426205 (-)
AKR/J MGP_AKRJ_G0022905
protein coding gene Chr16:83799939-83822126 (-)
BALB/cJ MGP_BALBcJ_G0022937
protein coding gene Chr16:81863947-81882956 (-)
C3H/HeJ MGP_C3HHeJ_G0022699
protein coding gene Chr16:84375732-84397260 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023384
protein coding gene Chr16:88058672-88082308 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020888
protein coding gene Chr16:79353155-79370424 (-)
CAST/EiJ MGP_CASTEiJ_G0022221
protein coding gene Chr16:84823319-84844338 (-)
CBA/J MGP_CBAJ_G0022668
protein coding gene Chr16:91815482-91835074 (-)
DBA/2J MGP_DBA2J_G0022802
protein coding gene Chr16:81286017-81304364 (-)
FVB/NJ MGP_FVBNJ_G0022777
protein coding gene Chr16:80484683-80503081 (-)
LP/J MGP_LPJ_G0022871
protein coding gene Chr16:84977865-85000852 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022796
protein coding gene Chr16:96264602-96285936 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023402
protein coding gene Chr16:84271947-84293580 (-)
PWK/PhJ MGP_PWKPhJ_G0021963
protein coding gene Chr16:81444362-81462068 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021793
protein coding gene Chr16:83777566-83795915 (-)
WSB/EiJ MGP_WSBEiJ_G0022269
protein coding gene Chr16:84526587-84550139 (-)



Homology
more
  • Human Ortholog
    MRPL39, mitochondrial ribosomal protein L39
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MRPL39, mitochondrial ribosomal protein L39
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C21orf92, L39mt, MRPL5, MRP-L5, MSTP003, PRED22, PRED66, RPML5
  • Links
    NCBI Gene ID: 54148
    neXtProt AC: NX_Q9NYK5
    UniProt: Q9NYK5

  • Chr Location
    21q21.3; chr21:25585656-25607858 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9679
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MRPL39
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022889 Ensembl Gene Model | MGI Sequence Detail 18167 C57BL/6J ±  kb
transcript ENSMUST00000116584 Ensembl | MGI Sequence Detail 2294 Not Applicable  
polypeptide ENSMUSP00000112283 Ensembl | MGI Sequence Detail 336 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 75
    cDNA 73
    Primer pair 1
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1889207
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:58917 O'Brien TW, et al., Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences. J Biol Chem. 1999 Dec 17;274(51):36043-51
  • Latest
    J:262380 Watson-Scales S, et al., Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018 May;14(5):e1007383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory