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Txnl4a Gene Detail
Summary
  • Symbol
    Txnl4a
  • Name
    thioredoxin-like 4A
  • Synonyms
    D18Wsu98e, ENSMUSG00000057130, Txnl4, U5-15kDa
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351613
    NCBI Gene: 27366
  • Gene Overview
    MyGene.info: TXNL4A
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:80206795-80223533 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 53.34 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    325 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351613
protein coding gene Chr18:80206794-80225851 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024592
protein coding gene Chr18:81114019-81132307 (+)
A/J MGP_AJ_G0024559
protein coding gene Chr18:77559186-77576079 (+)
AKR/J MGP_AKRJ_G0024530
protein coding gene Chr18:79885823-79905277 (+)
BALB/cJ MGP_BALBcJ_G0024557
protein coding gene Chr18:77745468-77763433 (+)
C3H/HeJ MGP_C3HHeJ_G0024326
protein coding gene Chr18:79968658-79985809 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025004
protein coding gene Chr18:83196613-83213270 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022435
protein coding gene Chr18:76415907-76432161 (+)
CAST/EiJ MGP_CASTEiJ_G0023799
protein coding gene Chr18:80301649-80318144 (+)
CBA/J MGP_CBAJ_G0024296
protein coding gene Chr18:86226906-86246138 (+)
DBA/2J MGP_DBA2J_G0024426
protein coding gene Chr18:77113040-77129494 (+)
FVB/NJ MGP_FVBNJ_G0024392
protein coding gene Chr18:76432453-76449365 (+)
LP/J MGP_LPJ_G0024510
protein coding gene Chr18:80984148-81000626 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024422
protein coding gene Chr18:87465409-87494353 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025053
protein coding gene Chr18:80026501-80043626 (+)
PWK/PhJ MGP_PWKPhJ_G0023544
protein coding gene Chr18:77508435-77526962 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023350
protein coding gene Chr18:80205040-80222624 (+)
WSB/EiJ MGP_WSBEiJ_G0023861
protein coding gene Chr18:79978836-79996712 (+)



Homology
more
  • Human Ortholog
    TXNL4A, thioredoxin like 4A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TXNL4A, thioredoxin like 4A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BMKS, DIB1, DIM1, SNRNP15, TXNL4, U5-15kD
  • Links
    NCBI Gene ID: 10907
    neXtProt AC: NX_P83876
    UniProt: P83876

  • Chr Location
    18q23; chr18:79972867-80033935 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7150
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TXNL4A
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057130 Ensembl Gene Model | MGI Sequence Detail 16739 C57BL/6J ±  kb
transcript ENSMUST00000145963 Ensembl | MGI Sequence Detail 1756 Not Applicable  
polypeptide ENSMUSP00000115320 Ensembl | MGI Sequence Detail 142 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-33954, MGI:106262, MGI:3642561
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory