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Dusp13 Gene Detail
Summary
  • Symbol
    Dusp13
  • Name
    dual specificity phosphatase 13
  • Synonyms
    LMW-DSP6, LOC382853, TMDP, TS-DSP6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351599
    NCBI Gene: 27389
  • Gene Overview
    MyGene.info: DUSP13
Location & Maps
more
  • Sequence Map
    Chr14:21733394-21751181 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      17788 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 11.85 cM, cytoband B
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    DUSP13, dual specificity phosphatase 13
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DUSP13, dual specificity phosphatase 13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BEDP, DUSP13A, DUSP13B, MDSP, SKRP4, TMDP
  • Links
    NCBI Gene ID: 51207
    neXtProt AC: NX_Q6B8I1, NX_Q9UII6

  • Chr Location
    10q22.2; chr10:75094432-75109221 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    9
  • Tissues
    4
  • cDNA Data
    7
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027823 VEGA Gene Model | MGI Sequence Detail 17788 C57BL/6J ±  kb
transcript OTTMUST00000068875 VEGA | MGI Sequence Detail 1342 Not Applicable  
polypeptide OTTMUSP00000034909 VEGA | MGI Sequence Detail 316 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    154 from dbSNP Build 142
Protein
Information
less
  • UniProt
    12 Sequences
  • Protein Ontology
    PR:000006740 dual specificity protein phosphatase 13
  • EC
    3.1.3.16, 3.1.3.48
  • InterPro Domains
    IPR020417 Atypical dual specificity phosphatase
    IPR020405 Atypical dual specificity phosphatase, subfamily A
    IPR024950 Dual specificity phosphatase
    IPR000340 Dual specificity phosphatase, catalytic domain
    IPR020422 Dual specificity protein phosphatase domain
    IPR016130 Protein-tyrosine phosphatase, active site
    IPR003595 Protein-tyrosine phosphatase, catalytic
    IPR029021 Protein-tyrosine phosphatase-like
    IPR000387 Tyrosine specific protein phosphatases domain
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 4
Other
Accession IDs
less
MGI:2686049
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:59256 Nakamura K, et al., Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis. Biochem J. 1999 Dec 15;344 Pt 3:819-25
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory