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Dusp13 Gene Detail
Summary
  • Symbol
    Dusp13
  • Name
    dual specificity phosphatase 13
  • Synonyms
    LMW-DSP6, LOC382853, TMDP, TS-DSP6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351599
    NCBI Gene: 27389
  • Gene Overview
    MyGene.info: DUSP13
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:21733395-21748651 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 11.85 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351599
 protein coding gene Chr14:21733394-21751181 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021054
 protein coding gene Chr14:14574783-14593264 (-)
A/J MGP_AJ_G0021003
 protein coding gene Chr14:14191767-14209554 (-)
AKR/J MGP_AKRJ_G0020980
 protein coding gene Chr14:14756591-14774436 (-)
BALB/cJ MGP_BALBcJ_G0021006
 protein coding gene Chr14:14298755-14316518 (-)
C3H/HeJ MGP_C3HHeJ_G0020790
 protein coding gene Chr14:14681274-14699485 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021439
 protein coding gene Chr14:15056672-15074459 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019007
 protein coding gene Chr14:14506048-14524602 (-)
CAST/EiJ MGP_CASTEiJ_G0020314
 protein coding gene Chr14:14486646-14508117 (-)
CBA/J MGP_CBAJ_G0020756
 protein coding gene Chr14:15825432-15848675 (-)
DBA/2J MGP_DBA2J_G0020879
 protein coding gene Chr14:14027383-14045107 (-)
FVB/NJ MGP_FVBNJ_G0020862
 protein coding gene Chr14:13914119-13932397 (-)
LP/J MGP_LPJ_G0020955
 protein coding gene Chr14:14782093-14801564 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020888
 protein coding gene Chr14:15581150-15602100 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021472
 protein coding gene Chr14:14535208-14554286 (-)
PWK/PhJ MGP_PWKPhJ_G0020063
 protein coding gene Chr14:13613843-13632513 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019885
 protein coding gene Chr14:14353537-14371554 (-)
WSB/EiJ MGP_WSBEiJ_G0020370
 protein coding gene Chr14:14529451-14547271 (-)



Homology
more
  • Human Ortholog
    DUSP13, dual specificity phosphatase 13
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DUSP13, dual specificity phosphatase 13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BEDP, DUSP13A, DUSP13B, MDSP, SKRP4, TMDP
  • Links
    NCBI Gene ID: 51207
    neXtProt AC: NX_Q6B8I1, NX_Q9UII6
    UniProt: Q6B8I1, Q9UII6

  • Chr Location
    10q22.2; chr10:75094432-75109221 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    640
  • Tissues
    4
  • cDNA Data
    8
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27389 NCBI Gene Model | MGI Sequence Detail 15257 C57BL/6J ±  kb
transcript NM_001007268 RefSeq | MGI Sequence Detail 1745 Not Specified  
polypeptide Q9QYJ7 UniProt | EBI | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 4
Other
Accession IDs
less
MGI:2686049
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:59256 Nakamura K, et al., Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis. Biochem J. 1999 Dec 15;344 Pt 3:819-25
  • Latest
    J:274697 Celaya AM, et al., Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss. Elife. 2019 Apr 2;8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/13/2020
MGI 6.16 		The Jackson Laboratory