Nup62
Gene Detail

Symbol Name ID

Nup62 nucleoporin 62 MGI:1351500

Synonyms

D7Ertd649e, Nupc1, p62

Feature Type

protein coding gene

Genetic Map

Chromosome 7

28.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:44816088-44830809 bp, + strand From VEGA annotation of GRCm38   14722 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68773  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Nup62

Human homologs

Human Homolog		NUP62, nucleoporin 62kDa
NCBI Gene ID		23636
neXtProt AC		NX_P37198
Human Synonyms		IBSN, p62, SNDI
Human Chr (Location)		19q13.33; chr19:50410082-50432988 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human NUP62

Alleles and phenotypes

All alleles(3) : Targeted(2) Transgenic(1)
 

Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7.

 

Gene Ontology (GO) classifications

All GO classifications: (32 annotations)

Process	cell aging, cell death, ...
Component	cytoplasm, cytoskeleton, ...
Function	PTB domain binding, receptor signaling complex scaffold activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (3)    Tissues (1)   
Theiler Stages: 15

Assay Type	Results
Western blot	3

cDNA source data(23)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(23) Primer pair(1)
Microarray probesets(9)

Other database links

VEGA Gene Model	OTTMUSG00000021116 (Evidence)
Ensembl Gene Model	ENSMUSG00000043858 (Evidence)
Entrez Gene	18226 (Evidence)
DFCI	TC1571859, TC1662207, TC1735150, TC1748436
DoTS	DT.110992273, DT.110992460, DT.533945, DT.91354306, DT.91411852
NIA Mouse Gene Index	U008053
Consensus CDS Project	CCDS21216.1
International Mouse Knockout Project Status	Nup62

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021116	VEGA Gene Model | MGI Sequence Detail	14722	C57BL/6J
transcript	OTTMUST00000049972	VEGA | MGI Sequence Detail	2719	Not Applicable
polypeptide	OTTMUSP00000023256	VEGA | MGI Sequence Detail	526	Not Applicable

All sequences(67) RefSeq(2) UniProt(8)

Polymorphisms

SNPs(58 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007758	Nucleoporin, NSP1-like, C-terminal
InterPro	IPR026010	Nucleoporin NSP1/NUP62
Protein Ontology	PR:000011521	nuclear pore glycoprotein p62

References

(Earliest) J:11463 Cordes V, et al., Nuclear pore complex glycoprotein p62 of Xenopus laevis and mouse: cDNA cloning and identification of its glycosylated region. Eur J Cell Biol. 1991 Jun;55(1):31-47
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(44)

Other accession IDs

MGD-MRK-35636, MGI:107175, MGI:1277198, MGI:2141843, MGI:2141941, MGI:2142031, MGI:2142164