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Nup62
Gene Detail
Symbol

Name
ID
Nup62
nucleoporin 62
MGI:1351500
Synonyms
D7Ertd649e, Nupc1, p62
Feature Type
protein coding gene
Genetic Map
Chromosome 7
28.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:44816088-44830809 bp, + strand
From VEGA annotation of GRCm38

  14722 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68773  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: NUP62
Gene Tree: Nup62

Human
homologs
NUP62, nucleoporin 62kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 23636
neXtProt AC: NX_P37198

Human Synonyms: IBSN, p62, SNDI

Human Chr (Location): 19q13.33; chr19:49906825-49929731 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NUP62

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(2) Transgenic(1)
 
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7.
 
Interactions
Nup62 interacts with 98 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (38 annotations)
Process cell aging, cell death, ...
Component cytoplasm, cytoskeleton, ...
Function kinesin binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (5)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 1
Western blot 4
cDNA source data(24)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase nup62cl    NEW 
Molecular
reagents
All nucleic(26) cDNA(24) Primer pair(2)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000021116 (Evidence)
Ensembl Gene Model ENSMUSG00000043858 (Evidence)
Entrez Gene 18226 (Evidence)
DFCI TC1571859, TC1662207, TC1735150, TC1748436
DoTS DT.110992273, DT.110992460, DT.533945, DT.91354306, DT.91411852
NIA Mouse Gene Index U008053
Consensus CDS Project CCDS21216.1
International Mouse Phenotyping Consortium Status Nup62
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021116 VEGA Gene Model | MGI Sequence Detail 14722 C57BL/6J ±  kb
transcript OTTMUST00000049972 VEGA | MGI Sequence Detail 2719 Not Applicable 
polypeptide OTTMUSP00000023256 VEGA | MGI Sequence Detail 526 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(2) UniProt(8)
Polymorphisms
SNPs within 2kb(119 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007758 Nucleoporin, NSP1-like, C-terminal
InterPro IPR026010 Nucleoporin NSP1/NUP62
Protein Ontology PR:000011521 nuclear pore glycoprotein p62
References
(Earliest) J:11463 Cordes V, et al., Nuclear pore complex glycoprotein p62 of Xenopus laevis and mouse: cDNA cloning and identification of its glycosylated region. Eur J Cell Biol. 1991 Jun;55(1):31-47
(Latest) J:187070 Beaslas O, et al., Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity. Exp Cell Res. 2012 Sep 10;318(15):1933-45
All references(45)
Other
accession IDs
MGD-MRK-35636, MGI:107175, MGI:1277198, MGI:2141843, MGI:2141941, MGI:2142031, MGI:2142164

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory