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Nufip1 Gene Detail
Summary
  • Symbol
    Nufip1
  • Name
    nuclear fragile X mental retardation protein interacting protein 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351474
    NCBI Gene: 27275
  • Gene Overview
    MyGene.info: NUFIP1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:76110891-76137379 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 40.35 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    216 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351474
protein coding gene Chr14:76110891-76137379 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021579
protein coding gene Chr14:71016670-71043525 (+)
A/J MGP_AJ_G0021537
protein coding gene Chr14:69378467-69404955 (+)
AKR/J MGP_AKRJ_G0021514
protein coding gene Chr14:71449496-71476550 (+)
BALB/cJ MGP_BALBcJ_G0021544
protein coding gene Chr14:69170503-69196991 (+)
C3H/HeJ MGP_C3HHeJ_G0021321
protein coding gene Chr14:71170353-71197501 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021984
protein coding gene Chr14:74112886-74139374 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019522
protein coding gene Chr14:66989677-67018244 (+)
CAST/EiJ MGP_CASTEiJ_G0020838
protein coding gene Chr14:67864541-67892340 (+)
CBA/J MGP_CBAJ_G0021289
protein coding gene Chr14:76493563-76521391 (+)
DBA/2J MGP_DBA2J_G0021412
protein coding gene Chr14:68782217-68808690 (+)
FVB/NJ MGP_FVBNJ_G0021390
protein coding gene Chr14:68123720-68150203 (+)
LP/J MGP_LPJ_G0021482
protein coding gene Chr14:72158907-72185445 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021417
protein coding gene Chr14:75194942-75221408 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022007
protein coding gene Chr14:70731127-70757545 (+)
PWK/PhJ MGP_PWKPhJ_G0020581
protein coding gene Chr14:65527706-65554500 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020418
protein coding gene Chr14:66687108-66714782 (+)
WSB/EiJ MGP_WSBEiJ_G0020891
protein coding gene Chr14:71066615-71093100 (+)



Homology
more
  • Human Ortholog
    NUFIP1, nuclear FMR1 interacting protein 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    NUFIP1, nuclear FMR1 interacting protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA540M5.1, NUFIP
  • Links
    NCBI Gene ID: 26747
    neXtProt AC: NX_Q9UHK0
    UniProt: Q9UHK0

  • Chr Location
    13q14.12; chr13:44939249-44989478 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 27275 NCBI Gene Model | MGI Sequence Detail 26489 C57BL/6J ±  kb
transcript NM_013745 RefSeq | MGI Sequence Detail 3974 C57BL/6  
polypeptide Q9QXX8 UniProt | EBI | MGI Sequence Detail 484 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000011501 nuclear fragile X mental retardation-interacting protein 1
  • InterPro Domains
    IPR019496 Nuclear fragile X mental retardation-interacting protein 1, conserved domain
    IPR039136 NUFIP1-like
    IPR013087 Zinc finger C2H2-type
    IPR022755 Zinc finger, double-stranded RNA binding
Molecular
Reagents
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  • All nucleic 61
    cDNA 60
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:58813 Bardoni B, et al., A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein. Hum Mol Genet. 1999 Dec;8(13):2557-66
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory