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Rpl13a Gene Detail
Summary
  • Symbol
    Rpl13a
  • Name
    ribosomal protein L13A
  • Synonyms
    1810026N22Rik, Tstap198-7, tum-antigen, tum-transplantation antigen P198
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351455
    NCBI Gene: 22121
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:44774987-44778169 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.14 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    75 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351455
protein coding gene Chr7:44774982-44778185 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032201
protein coding gene Chr7:45360925-45364023 (-)
A/J MGP_AJ_G0032180
protein coding gene Chr7:44498287-44501385 (-)
AKR/J MGP_AKRJ_G0032116
protein coding gene Chr7:45727746-45731155 (-)
BALB/cJ MGP_BALBcJ_G0032192
protein coding gene Chr7:44496759-44499939 (-)
C3H/HeJ MGP_C3HHeJ_G0031908
protein coding gene Chr7:46224258-46227356 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032684
protein coding gene Chr7:47629184-47633641 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029698
protein coding gene Chr7:47061819-47064937 (-)
CAST/EiJ MGP_CASTEiJ_G0031236
protein coding gene Chr7:37607943-37611863 (-)
CBA/J MGP_CBAJ_G0031872
protein coding gene Chr7:49186837-49191889 (-)
DBA/2J MGP_DBA2J_G0032030
protein coding gene Chr7:44167975-44175024 (-)
FVB/NJ MGP_FVBNJ_G0031981
protein coding gene Chr7:43945918-43949631 (-)
LP/J MGP_LPJ_G0032108
protein coding gene Chr7:46042097-46045277 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032018
protein coding gene Chr7:47905897-47909077 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032700
protein coding gene Chr7:44944104-44947284 (-)
PWK/PhJ MGP_PWKPhJ_G0030959
protein coding gene Chr7:37532779-37538048 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030796
protein coding gene Chr7:32956565-32960247 (-)
WSB/EiJ MGP_WSBEiJ_G0031353
protein coding gene Chr7:45434434-45439445 (-)



Homology
more
  • Human Ortholog
    RPL13A, ribosomal protein L13a
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPL13A, ribosomal protein L13a
  • Synonyms
    L13A, TSTA1, uL13
  • Links
    NCBI Gene ID: 23521
    neXtProt AC: NX_P40429
    UniProt: P40429

  • Chr Location
    19q13.33; chr19:49487510-49493057 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 2 alleles in 3 genetic backgrounds
    1 phenotype from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes lacking snoRNAs encoded by introns of this gene show altered mitochondrial metabolism, lower reactive oxygen species tone, enhanced glucose-stimulated insulin secretion and glucose tolerance, reduced oxidative stress responses in pancreatic islets, and resistance to diabetogenic stimuli.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22121 NCBI Gene Model | MGI Sequence Detail 3183 C57BL/6J ±  kb
    transcript NM_009438 RefSeq | MGI Sequence Detail 1039 Not Specified  
    polypeptide P19253 UniProt | EBI | MGI Sequence Detail 203 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 938
      Genomic 4
      cDNA 933
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-15284, MGI:1916425, MGI:98856
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 4
      Gene Ontology 11
      Phenotypes 10
    • Earliest
      J:23422 Sibille C, et al., Structure of the gene of tum- transplantation antigen P198: a point mutation generates a new antigenic peptide. J Exp Med. 1990 Jul 1;172(1):35-45
    • Latest
      J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory