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Ddx24 Gene Detail
Summary
  • Symbol
    Ddx24
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
  • Synonyms
    1700055J08Rik, 2510027P10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351337
    NCBI Gene: 27225
  • Gene Overview
    MyGene.info: DDX24
Location & Maps
more
  • Sequence Map
    Chr12:103407976-103425867 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17892 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    DDX24, DEAD-box helicase 24
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DDX24, DEAD-box helicase 24
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 57062
    neXtProt AC: NX_Q9GZR7

  • Chr Location
    14q32; chr14:94050922-94081212 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 10702
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: DDX24
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    9
  • Targeted
    2
  • Genomic Mutations
    1 involving Ddx24
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 27225 NCBI Gene Model | MGI Sequence Detail 17892 C57BL/6J ±  kb
transcript NM_001159502 RefSeq | MGI Sequence Detail 3070 C57BL/6  
polypeptide Q9ESV0 UniProt | EBI | MGI Sequence Detail 857 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    183 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000006360 ATP-dependent RNA helicase DDX24
  • EC
  • InterPro Domains
    IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
    IPR011545 DEAD/DEAH box helicase domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR014014 RNA helicase, DEAD-box type, Q motif
Molecular
Reagents
less
  • All nucleic 232
    cDNA 232

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919702, MGI:1925876, MGI:2144875
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:63823 Zhao Y, et al., Cloning and characterization of human DDX24 and mouse Ddx24, two novel putative DEAD-Box proteins, and mapping DDX24 to human chromosome 14q32. Genomics. 2000 Aug 1;67(3):351-5
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory