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Dbf4 Gene Detail
Summary
  • Symbol
    Dbf4
  • Name
    DBF4 zinc finger
  • Synonyms
    Ask
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351328
    NCBI Gene: 27214
  • Gene Overview
    MyGene.info: DBF4
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:8396973-8422716 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 3.43 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    318 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351328
protein coding gene Chr5:8396969-8422723 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029283
protein coding gene Chr5:5351763-5377709 (-)
A/J MGP_AJ_G0029246
protein coding gene Chr5:5215979-5241702 (-)
AKR/J MGP_AKRJ_G0029195
protein coding gene Chr5:5334090-5360026 (-)
BALB/cJ MGP_BALBcJ_G0029263
protein coding gene Chr5:5404351-5430016 (-)
C3H/HeJ MGP_C3HHeJ_G0028983
protein coding gene Chr5:5521532-5547234 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029713
protein coding gene Chr5:5873190-5901410 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026956
protein coding gene Chr5:5031541-5032026 (-)
CAST/EiJ MGP_CASTEiJ_G0028396
protein coding gene Chr5:5383516-5409185 (-)
CBA/J MGP_CBAJ_G0028944
protein coding gene Chr5:5982354-6008067 (-)
DBA/2J MGP_DBA2J_G0029098
protein coding gene Chr5:5322445-5350866 (-)
FVB/NJ MGP_FVBNJ_G0029060
protein coding gene Chr5:5122447-5148648 (-)
LP/J MGP_LPJ_G0029187
protein coding gene Chr5:5490386-5520513 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029087
protein coding gene Chr5:6009594-6035998 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029744
protein coding gene Chr5:5317992-5343852 (-)
PWK/PhJ MGP_PWKPhJ_G0028118
protein coding gene Chr5:5123222-5149044 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0028476
protein coding gene Chr5:5321783-5348233 (-)



Homology
more
  • Human Ortholog
    DBF4, DBF4 zinc finger
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DBF4, DBF4 zinc finger
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ASK, CHIF, DBF4A, ZDBF1
  • Links
    NCBI Gene ID: 10926
    neXtProt AC: NX_Q9UBU7
    UniProt: Q9UBU7

  • Chr Location
    7q21.12; chr7:87876229-87909541 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002297 Ensembl Gene Model | MGI Sequence Detail 25744 C57BL/6J ±  kb
transcript ENSMUST00000171808 Ensembl | MGI Sequence Detail 2402 Not Applicable  
polypeptide ENSMUSP00000132906 Ensembl | MGI Sequence Detail 663 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 91
    Genomic 1
    cDNA 89
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140773
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:58256 Lepke M, et al., Identification, characterization and chromosomal localization of the cognate human and murine DBF4 genes. Mol Gen Genet. 1999 Sep;262(2):220-9
  • Latest
    J:246066 Sundberg JP, et al., Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One. 2017;12(7):e0180682

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory