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Sgk2 Gene Detail
Summary
  • Symbol
    Sgk2
  • Name
    serum/glucocorticoid regulated kinase 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351318
    NCBI Gene: 27219
  • Gene Overview
    MyGene.info: SGK2
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:162987330-163014127 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 83.93 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    240 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351318
protein coding gene Chr2:162987300-163014139 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026815
protein coding gene Chr2:168274450-168301114 (+)
A/J MGP_AJ_G0026781
protein coding gene Chr2:161522825-161550769 (+)
AKR/J MGP_AKRJ_G0026752
protein coding gene Chr2:166284188-166314878 (+)
BALB/cJ MGP_BALBcJ_G0026790
protein coding gene Chr2:161842170-161869244 (+)
C3H/HeJ MGP_C3HHeJ_G0026532
protein coding gene Chr2:166635934-166665223 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027238
protein coding gene Chr2:173217157-173249070 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024608
protein coding gene Chr2:154816576-154842393 (+)
CAST/EiJ MGP_CASTEiJ_G0025993
protein coding gene Chr2:166992249-167021317 (+)
CBA/J MGP_CBAJ_G0026509
protein coding gene Chr2:179484877-179517731 (+)
DBA/2J MGP_DBA2J_G0026647
protein coding gene Chr2:160693313-160719162 (+)
FVB/NJ MGP_FVBNJ_G0026613
protein coding gene Chr2:159060631-159086637 (+)
LP/J MGP_LPJ_G0026750
protein coding gene Chr2:168420019-168444945 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026635
protein coding gene Chr2:183165296-183194618 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027294
protein coding gene Chr2:166172945-166201052 (+)
PWK/PhJ MGP_PWKPhJ_G0025727
protein coding gene Chr2:160240235-160266172 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025530
protein coding gene Chr2:165036270-165061146 (+)
WSB/EiJ MGP_WSBEiJ_G0026063
protein coding gene Chr2:167037709-167063186 (+)



Homology
more
  • Human Ortholog
    SGK2, SGK2, serine/threonine kinase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SGK2, SGK2, serine/threonine kinase 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    dJ138B7.2, H-SGK2
  • Links
    NCBI Gene ID: 10110
    neXtProt AC: NX_Q9HBY8
    UniProt: Q9HBY8

  • Chr Location
    20q13.12; chr20:43558995-43585633 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8446
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SGK2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000017868 Ensembl Gene Model | MGI Sequence Detail 26798 C57BL/6J ±  kb
transcript ENSMUST00000018012 Ensembl | MGI Sequence Detail 2693 Not Applicable  
polypeptide ENSMUSP00000018012 Ensembl | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138835, MGI:2139321
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:58667 Kobayashi T, et al., Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. Biochem J. 1999 Nov 15;344 Pt 1:189-97
  • Latest
    J:235644 Wu Y, et al., Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. PLoS Genet. 2016 Sep;12(9):e1006355

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory