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Sgk2 Gene Detail
Summary
  • Symbol
    Sgk2
  • Name
    serum/glucocorticoid regulated kinase 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351318
    NCBI Gene: 27219
  • Gene Overview
    MyGene.info: SGK2
Location & Maps
more
  • Sequence Map
    Chr2:162987330-163014127 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26798 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 83.93 cM, cytoband H3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SGK2, SGK2, serine/threonine kinase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SGK2, SGK2, serine/threonine kinase 2
    Orthology source: HomoloGene
  • Synonyms
    dJ138B7.2, H-SGK2
  • Links
    NCBI Gene ID: 10110
    neXtProt AC: NX_Q9HBY8

  • Chr Location
    20q13.2; chr20:43558995-43585633 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8446
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SGK2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001152 VEGA Gene Model | MGI Sequence Detail 26798 C57BL/6J ±  kb
transcript OTTMUST00000002245 VEGA | MGI Sequence Detail 2693 Not Applicable  
polypeptide OTTMUSP00000001094 VEGA | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    240 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138835, MGI:2139321
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:58667 Kobayashi T, et al., Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. Biochem J. 1999 Nov 15;344 Pt 1:189-97
  • Latest
    J:213153 Harms MJ, et al., Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory