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Asns
Gene Detail
Symbol

Name
ID
Asns
asparagine synthetase
MGI:1350929
Feature Type
protein coding gene
Genetic Map
Chromosome 6
3.31 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:7675169-7693254 bp, - strand
From VEGA annotation of GRCm38

  18086 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69113  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Asn_synthetase_glu-h
Gene Tree: Asns

Human
homologs
Human Homolog ASNS, asparagine synthetase (glutamine-hydrolyzing)
NCBI Gene ID 440
neXtProt AC  NX_P08243
Human Synonyms  ASNSD, TS11
Human Chr (Location)  7q21.3; chr7:97852117-97872542 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ASNS
Mutations,
alleles, and
phenotypes
All mutations/alleles(23) : Gene trapped(21) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Asns interacts with 33 markers (Mir22, Mir29a, Mir34a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (365)    Tissues (121)    Images (33)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 365
cDNA source data(213)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(213) cDNA(213)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022779 (Evidence)
Ensembl Gene ModelENSMUSG00000029752 (Evidence)
Entrez Gene27053 (Evidence)
UniGene2942
DFCITC1633632, TC1572021
DoTSDT.101317157
NIA Mouse Gene IndexU027034
EC6.3.5.4
Consensus CDS ProjectCCDS19907.1
International Mouse Knockout Project StatusAsns
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022779 VEGA Gene Model | MGI Sequence Detail 18086 C57BL/6J ±  kb
transcript OTTMUST00000054696 VEGA | MGI Sequence Detail 2001 Not Applicable 
polypeptide OTTMUSP00000026130 VEGA | MGI Sequence Detail 561 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(6) UniProt(11)
Polymorphisms
SNPs within 2kb(345 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001962 Asparagine synthase
InterPro IPR006426 Asparagine synthase, glutamine-hydrolyzing
InterPro IPR000583 Class II glutamine amidotransferase domain
InterPro IPR017932 Glutamine amidotransferase type 2 domain
InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Protein Ontology PR:000004377 asparagine synthetase [glutamine-hydrolyzing]
References
(Earliest) J:58768 Goodwin L, et al., Patterns of expression of asparagine synthetase mRNA in various human leukemic and carcinoma cell lines. Proc Am Soc Human Genet. 1994;55:325 (Abstr.)
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory