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Aoah
Gene Detail
Symbol

Name
ID
Aoah
acyloxyacyl hydrolase
MGI:1350928
Synonyms
4930433E13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 13
7.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:20794119-21024252 bp, + strand
From Ensembl annotation of GRCm38

  230134 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1238  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: AOAH
Protein SuperFamily: acyloxyacyl hydrolase
Gene Tree: Aoah

Human
homologs
AOAH, acyloxyacyl hydrolase (neutrophil)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 313
neXtProt AC: NX_P28039

Human Chr (Location): 7p14.2; chr7:36512941-36724549 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(23) Radiation induced(1) Targeted(2)
Genomic Mutations involving Aoah (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice have a reduced ability to deacylate bacterial lipopolysaccharides.
 
Interactions
Aoah interacts with 133 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
cDNA source data(20)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase aoah    NEW 
Molecular
reagents
All nucleic(21) cDNA(21)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000021322 (Evidence)
Entrez Gene 27052 (Evidence)
UniGene 314046
DFCI TC1595937, TC1583135
DoTS DT.101340905, DT.101399752, DT.94129408, DT.55168601, DT.91308816
NIA Mouse Gene Index U375713, U014590
EC 3.1.1.77
Consensus CDS Project CCDS26266.1
International Mouse Phenotyping Consortium Status Aoah
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021322 Ensembl Gene Model | MGI Sequence Detail 230134 C57BL/6J ±  kb
transcript ENSMUST00000021757 Ensembl | MGI Sequence Detail 2915 Not Applicable 
polypeptide ENSMUSP00000021757 Ensembl | MGI Sequence Detail 574 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(12) UniProt(7)
Polymorphisms
SNPs within 2kb(2314 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2334)
Protein-related
information
ResourceIDDescription
InterPro IPR001087 Lipase, GDSL
InterPro IPR008139 Saposin B
InterPro IPR011001 Saposin-like
InterPro IPR008138 Saposin-like type B, 2
Protein Ontology PR:000004085 acyloxyacyl hydrolase
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:206287 Janelsins BM, et al., Altered inactivation of commensal LPS due to acyloxyacyl hydrolase deficiency in colonic dendritic cells impairs mucosal Th17 immunity. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):373-8
All references(38)
Other
accession IDs
MGI:1921929

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory