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Aoah Gene Detail
Summary
  • Symbol
    Aoah
  • Name
    acyloxyacyl hydrolase
  • Synonyms
    4930433E13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1350928
    NCBI Gene: 27052
  • Gene Overview
    MyGene.info: AOAH
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:20794113-21036617 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 7.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2428 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1350928
protein coding gene Chr13:20794103-21036617 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020265
protein coding gene Chr13:18020630-18261671 (+)
A/J MGP_AJ_G0020222
protein coding gene Chr13:17655038-17864547 (+)
AKR/J MGP_AKRJ_G0020196
protein coding gene Chr13:17923930-18152652 (+)
BALB/cJ MGP_BALBcJ_G0020208
protein coding gene Chr13:17705942-17926206 (+)
C3H/HeJ MGP_C3HHeJ_G0020011
protein coding gene Chr13:18029772-18258748 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020652
protein coding gene Chr13:18664717-18904615 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018259
protein coding gene Chr13:16057956-16260991 (+)
CAST/EiJ MGP_CASTEiJ_G0019546
protein coding gene Chr13:17815511-18044687 (+)
CBA/J MGP_CBAJ_G0019975
protein coding gene Chr13:19323923-19563398 (+)
DBA/2J MGP_DBA2J_G0020094
protein coding gene Chr13:17275335-17496206 (+)
FVB/NJ MGP_FVBNJ_G0020076
protein coding gene Chr13:16938512-17173278 (+)
LP/J MGP_LPJ_G0020165
protein coding gene Chr13:18260900-18506715 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020114
protein coding gene Chr13:19736764-19973655 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020681
protein coding gene Chr13:17751832-17988259 (+)
PWK/PhJ MGP_PWKPhJ_G0019309
protein coding gene Chr13:17341135-17555988 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019115
protein coding gene Chr13:16770131-16998477 (+)
WSB/EiJ MGP_WSBEiJ_G0019605
protein coding gene Chr13:17810218-18055995 (+)



Homology
more
  • Human Ortholog
    AOAH, acyloxyacyl hydrolase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AOAH, acyloxyacyl hydrolase
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 313
    neXtProt AC: NX_P28039
    UniProt: P28039

  • Chr Location
    7p14.2; chr7:36512042-36724549 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice have a reduced ability to deacylate bacterial lipopolysaccharides.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021322 Ensembl Gene Model | MGI Sequence Detail 242505 C57BL/6J ±  kb
transcript ENSMUST00000021757 Ensembl | MGI Sequence Detail 2921 Not Applicable  
polypeptide ENSMUSP00000021757 Ensembl | MGI Sequence Detail 574 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 5
Other
Accession IDs
less
MGI:1921929
References
more
  • Summaries
    All 48
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 23
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:262155 Yang W, et al., Acyloxyacyl hydrolase modulates pelvic pain severity. Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R353-R365

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory