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Etv3 Gene Detail
Summary
  • Symbol
    Etv3
  • Name
    ets variant 3
  • Synonyms
    ETS-domain transcriptional repressor, METS, Pe1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1350926
    NCBI Gene: 27049
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:87432891-87447463 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 38.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    382 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1350926
 protein coding gene Chr3:87432714-87447463 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027364
 protein coding gene Chr3:87626760-87641481 (+)
A/J MGP_AJ_G0027328
 protein coding gene Chr3:84666725-84681452 (+)
AKR/J MGP_AKRJ_G0027294
 protein coding gene Chr3:86703566-86718248 (+)
BALB/cJ MGP_BALBcJ_G0027337
 protein coding gene Chr3:84744148-84758848 (+)
C3H/HeJ MGP_C3HHeJ_G0027080
 protein coding gene Chr3:87003751-87018471 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027783
 protein coding gene Chr3:90856850-90871599 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025136
 protein coding gene Chr3:80284727-80299305 (+)
CAST/EiJ MGP_CASTEiJ_G0026527
 protein coding gene Chr3:87218498-87233212 (+)
CBA/J MGP_CBAJ_G0027055
 protein coding gene Chr3:93927039-93941759 (+)
DBA/2J MGP_DBA2J_G0027191
 protein coding gene Chr3:84150056-84164741 (+)
FVB/NJ MGP_FVBNJ_G0027160
 protein coding gene Chr3:82429041-82443761 (+)
LP/J MGP_LPJ_G0027299
 protein coding gene Chr3:88579370-88594092 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027179
 protein coding gene Chr3:100192785-100208291 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027841
 protein coding gene Chr3:86479452-86494170 (+)
PWK/PhJ MGP_PWKPhJ_G0026260
 protein coding gene Chr3:83948073-83962786 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026077
 protein coding gene Chr3:85667177-85684112 (+)
WSB/EiJ MGP_WSBEiJ_G0026606
 protein coding gene Chr3:86844347-86859069 (+)



Homology
more
  • Human Ortholog
    ETV3, ETS variant transcription factor 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ETV3, ETS variant transcription factor 3
  • Synonyms
    METS, PE-1, PE1
  • Links
    NCBI Gene ID: 2117
    UniProt: P41162

  • Chr Location
    1q23.1; chr1:157121191-157138474 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    824
  • Tissues
    92
  • cDNA Data
    17
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27049 NCBI Gene Model | MGI Sequence Detail 14573 C57BL/6J ±  kb
transcript NM_001286844 RefSeq | MGI Sequence Detail 5451 C57BL/6  
polypeptide Q8R4Z4 UniProt | EBI | MGI Sequence Detail 513 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 17
    Primer pair 1
    Other 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:2139692
References
more
  • Summaries
    All 52
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:17414 Klemsz M, et al., PE-1, a novel ETS oncogene family member, localizes to chromosome 1q21-q23. Genomics. 1994 Mar 15;20(2):291-4
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory