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Sh3d19 Gene Detail
Summary
  • Symbol
    Sh3d19
  • Name
    SH3 domain protein D19
  • Synonyms
    Kryn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1350923
    NCBI Gene: 27059
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:85878416-86037833 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 37.83 cM, cytoband F1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1362 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1350923
protein coding gene Chr3:85878112-86037833 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027351
protein coding gene Chr3:86000485-86164640 (+)
A/J MGP_AJ_G0027315
protein coding gene Chr3:83091849-83249804 (+)
AKR/J MGP_AKRJ_G0027281
protein coding gene Chr3:85065241-85250732 (+)
BALB/cJ MGP_BALBcJ_G0027324
protein coding gene Chr3:83176952-83336461 (+)
C3H/HeJ MGP_C3HHeJ_G0027068
protein coding gene Chr3:85389670-85549704 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027770
protein coding gene Chr3:89182945-89350118 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025123
protein coding gene Chr3:78740852-78897807 (+)
CAST/EiJ MGP_CASTEiJ_G0026515
protein coding gene Chr3:85584142-85753562 (+)
CBA/J MGP_CBAJ_G0027043
protein coding gene Chr3:92166982-92339714 (+)
DBA/2J MGP_DBA2J_G0027179
protein coding gene Chr3:82588527-82747475 (+)
FVB/NJ MGP_FVBNJ_G0027147
protein coding gene Chr3:80891635-81052540 (+)
LP/J MGP_LPJ_G0027287
protein coding gene Chr3:86934487-87101784 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027166
protein coding gene Chr3:98442248-98613512 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027828
protein coding gene Chr3:84867614-85032633 (+)
PWK/PhJ MGP_PWKPhJ_G0026249
protein coding gene Chr3:82397173-82561708 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026065
protein coding gene Chr3:84028663-84192133 (+)
WSB/EiJ MGP_WSBEiJ_G0026593
protein coding gene Chr3:85241001-85401098 (+)



Homology
more
  • Human Ortholog
    SH3D19, SH3 domain containing 19
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SH3D19, SH3 domain containing 19
  • Synonyms
    EBP, Eve-1, EVE1, Kryn, SH3P19
  • Links
    NCBI Gene ID: 152503
    neXtProt AC: NX_Q5HYK7
    UniProt: Q5HYK7

  • Chr Location
    4q31.3; chr4:151102751-151325605 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028082 Ensembl Gene Model | MGI Sequence Detail 159418 C57BL/6J ±  kb
transcript ENSMUST00000238443 Ensembl | MGI Sequence Detail 7217 Not Applicable  
polypeptide ENSMUSP00000158699 Ensembl | MGI Sequence Detail 1065 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139947
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory