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Tspan32 Gene Detail
Summary
  • Symbol
    Tspan32
  • Name
    tetraspanin 32
  • Synonyms
    Art-1, D7Wsu37e, Phemx, Tspan32, Tssc6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1350360
    NCBI Gene: 27027
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:142558644-142573223 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 88.09 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    325 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1350360
 protein coding gene Chr7:142558644-142573381 (+)
129S1/SvImJ ENSMUSG00200040314
 protein coding gene Chr7:129125268-129139870 (+)
A/J ENSMUSG00195032348
 protein coding gene Chr7:133607373-133621969 (+)
AKR/J ENSMUSG00220026879
 protein coding gene Chr7:127089594-127104195 (+)
BALB/cJ ENSMUSG00180038798
 protein coding gene Chr7:130288218-130302783 (+)
C3H/HeJ ENSMUSG00175037542
 protein coding gene Chr7:131028244-131042840 (+)
C57BL/6NJ ENSMUSG00215042260
 protein coding gene Chr7:130294607-130309205 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030733
 protein coding gene Chr7:145197822-145212735 (+)
CAST/EiJ ENSTCUG00005050387
 protein coding gene Chr7:133590501-133605049 (+)
CBA/J ENSMUSG00210027121
 protein coding gene Chr7:130786157-130800759 (+)
DBA/2J ENSMUSG00185013487
 protein coding gene Chr7:135064777-135079387 (+)
FVB/NJ ENSMUSG00205022069
 protein coding gene Chr7:130706891-130721490 (+)
JF1/MsJ ENSUMUG00000034401
 protein coding gene Chr7:140137531-140152084 (+)
LP/J ENSMUSG00230041936
 protein coding gene Chr7:141228066-141242665 (+)
NOD/ShiLtJ ENSMUSG00190025342
 protein coding gene Chr7:130893650-130908250 (+)
NZO/HlLtJ ENSMUSG00225049011
 protein coding gene Chr7:139436988-139451586 (+)
PWK/PhJ ENSLUMG00010045727
 protein coding gene Chr7:129274912-129289669 (+)
SPRET/EiJ ENSMSPG00010040775
 protein coding gene Chr7:130728634-130743188 (+)
WSB/EiJ ENSIUOG00005034518
 protein coding gene Chr7:131656916-131671514 (+)



Homology
more
  • Human Ortholog
    TSPAN32, tetraspanin 32
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSPAN32, tetraspanin 32
  • Synonyms
    PHEMX, PHMX, TSSC6
  • Links
    NCBI Gene ID: 10077
    UniProt: Q96QS1

  • Chr Location
    11p15.5; chr11:2301990-2318204 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap null mutation exhibit normal hematopoiesis, hemolytic and granulopoitic responses. B cells exhibit normal proliferative responses while T cells demonstrate enhanced proliferation upon T cell receptor stimulation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    52
  • cDNA Data
    30
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 27027 NCBI Gene Model | MGI Sequence Detail 14580 C57BL/6J ±  kb
    transcript NM_020286 RefSeq | MGI Sequence Detail 1697 ZRU/MplStud  
    polypeptide Q9JHH2 UniProt | EBI | MGI Sequence Detail 256 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 34
      cDNA 31
      Primer pair 3

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-34140, MGI:106446, MGI:1861715, MGI:2142216, MGI:2142302
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 10
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory