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Brd7
Gene Detail
Symbol

Name
ID
Brd7
bromodomain containing 7
MGI:1349766
Synonyms
BP75, bromodomain protein 75 kDa, CELTIX1
Feature Type
protein coding gene
Genetic Map
Chromosome 8
43.07 cM, cytoband C4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:88331039-88362194 bp, - strand
From VEGA annotation of GRCm38

  31156 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8085  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: BRD7
Gene Tree: Brd7

Human
homologs
BRD7, bromodomain containing 7
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 29117
neXtProt AC: NX_Q9NPI1

Human Synonyms: BP75, CELTIX1, NAG4

Human Chr (Location): 16q12; chr16:50319018-50368966 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Brd7 interacts with 234 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process cell cycle, negative regulation of cell proliferation, ...
Component BAF-type complex, nucleus
Function histone binding, lysine-acetylated histone binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (134)    Tissues (106)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 105
RT-PCR 29
cDNA source data(137)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase brd7 ; ZFIN brd7    NEW 
Molecular
reagents
All nucleic(143) cDNA(139) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000017292 (Evidence)
Ensembl Gene Model ENSMUSG00000031660 (Evidence)
Entrez Gene 26992 (Evidence)
UniGene 5400
DFCI TC1575302, TC1628562, TC1609452
DoTS DT.101307741, DT.94185153, DT.40144633
NIA Mouse Gene Index U030080
Consensus CDS Project CCDS22510.1
International Mouse Phenotyping Consortium Status Brd7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017292 VEGA Gene Model | MGI Sequence Detail 31156 C57BL/6J ±  kb
transcript OTTMUST00000041929 VEGA | MGI Sequence Detail 3625 Not Applicable 
polypeptide OTTMUSP00000018856 VEGA | MGI Sequence Detail 651 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(12) UniProt(4)
Polymorphisms
SNPs within 2kb(227 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
InterPro IPR021900 Protein of unknown function DUF3512
Protein Ontology PR:000004808 bromodomain-containing protein 7
References
(Earliest) J:58365 Cuppen E, et al., Identification and molecular characterization of BP75, a novel bromodomain-containing protein. FEBS Lett. 1999 Oct 15;459(3):291-8
(Latest) J:212358 Singh AP, et al., Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation. Nucleic Acids Res. 2014 Mar;42(5):2958-75
All references(46)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory