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Pabpc1 Gene Detail
Summary
  • Symbol
    Pabpc1
  • Name
    poly(A) binding protein, cytoplasmic 1
  • Synonyms
    Pabp1, Pabpl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349722
    NCBI Gene: 18458
Location & Maps
more
  • Sequence Map
    Chr15:36595661-36608973 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13313 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    PABPC1, poly(A) binding protein, cytoplasmic 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PABPC1, poly(A) binding protein, cytoplasmic 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PAB1, PABP, PABP1, PABPC2, PABPL1
  • Links
    NCBI Gene ID: 26986
    neXtProt AC: NX_P11940

  • Chr Location
    8q22.2-q23; chr8:100702916-100722998 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    31
  • Chemically induced (other)
    2
  • Gene trapped
    27
  • Targeted
    2
  • Genomic Mutations
    2 involving Pabpc1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019779 VEGA Gene Model | MGI Sequence Detail 13313 C57BL/6J ±  kb
transcript OTTMUST00000047296 VEGA | MGI Sequence Detail 2817 Not Applicable  
polypeptide OTTMUSP00000021349 VEGA | MGI Sequence Detail 636 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    84 from dbSNP Build 137
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000012204 polyadenylate-binding protein 1
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR006515 Polyadenylate binding protein, human types 1, 2, 3, 4
    IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein
    IPR000504 RNA recognition motif domain
Molecular
Reagents
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  • All nucleic 1112
    cDNA 1107
    Primer pair 4
    Other 1

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-13120, MGD-MRK-27031, MGI:104668
References
more
  • Summaries
    All 53
    Developmental Gene Expression 7
    Gene Ontology 10
    Phenotypes 13
  • Earliest
    J:10879 Rhyner TA, et al., Isolation of cDNAs from a mouse astroglial cell line by a subtracted cDNA library. J Neurosci Res. 1990 Oct;27(2):144-52
  • Latest
    J:216392 Kraushar ML, et al., Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3815-24

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory