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Pabpc1 Gene Detail
Summary
  • Symbol
    Pabpc1
  • Name
    poly(A) binding protein, cytoplasmic 1
  • Synonyms
    Pabp1, Pabpl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349722
    NCBI Gene: 18458
  • Gene Overview
    MyGene.info: PABPC1
  • Alliance
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:36595658-36609581 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 14.51 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349722
protein coding gene Chr15:36595658-36609668 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021796
protein coding gene Chr15:34984273-35001023 (-)
A/J MGP_AJ_G0021757
protein coding gene Chr15:33688735-33704774 (-)
AKR/J MGP_AKRJ_G0021736
protein coding gene Chr15:34620133-34633233 (-)
BALB/cJ MGP_BALBcJ_G0021764
protein coding gene Chr15:33692792-33705771 (-)
C3H/HeJ MGP_C3HHeJ_G0021538
protein coding gene Chr15:34584581-34599093 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022203
protein coding gene Chr15:36327411-36340817 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019740
protein coding gene Chr15:31495434-31510120 (-)
CAST/EiJ MGP_CASTEiJ_G0021054
protein coding gene Chr15:34979757-34996277 (-)
CBA/J MGP_CBAJ_G0021507
protein coding gene Chr15:37498430-37514897 (-)
DBA/2J MGP_DBA2J_G0021631
protein coding gene Chr15:33502066-33515261 (-)
FVB/NJ MGP_FVBNJ_G0021609
protein coding gene Chr15:32905818-32919564 (-)
LP/J MGP_LPJ_G0021700
protein coding gene Chr15:34903403-34916582 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021633
protein coding gene Chr15:40597227-40611568 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022226
protein coding gene Chr15:34765854-34779137 (-)
PWK/PhJ MGP_PWKPhJ_G0020798
protein coding gene Chr15:33531587-33545716 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020636
protein coding gene Chr15:34470636-34483540 (-)
WSB/EiJ MGP_WSBEiJ_G0021110
protein coding gene Chr15:34741649-34758164 (-)



Homology
more
  • Human Ortholog
    PABPC1, poly(A) binding protein cytoplasmic 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PABPC1, poly(A) binding protein cytoplasmic 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PAB1, PABP, PABP1, PABPC2, PABPL1
  • Links
    NCBI Gene ID: 26986
    neXtProt AC: NX_P11940
    UniProt: P11940

  • Chr Location
    8q22.3; chr8:100702916-100722998 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 18458 NCBI Gene Model | MGI Sequence Detail 13924 C57BL/6J ±  kb
transcript NM_008774 RefSeq | MGI Sequence Detail 2842 C57BL/6  
polypeptide P29341 UniProt | EBI | MGI Sequence Detail 636 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000012204 polyadenylate-binding protein 1
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR036053 PABC (PABP) domain
    IPR006515 Polyadenylate binding protein, human types 1, 2, 3, 4
    IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
    IPR003954 RNA recognition motif domain, eukaryote
Molecular
Reagents
less
  • All nucleic 1113
    cDNA 1108
    Primer pair 4
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-13120, MGD-MRK-27031, MGI:104668
References
more
  • Summaries
    All 74
    Developmental Gene Expression 8
    Gene Ontology 15
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:263402 Bayes A, et al., Evolution of complexity in the zebrafish synapse proteome. Nat Commun. 2017 Mar 2;8:14613

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory