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Pla2g2f Gene Detail
Summary
  • Symbol
    Pla2g2f
  • Name
    phospholipase A2, group IIF
  • Synonyms
    mGIIFsPLA2s
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349661
    NCBI Gene: 26971
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:138750533-138757598 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 70.56 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    164 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349661
protein coding gene Chr4:138750533-138757626 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029002
protein coding gene Chr4:141535494-141542587 (-)
A/J MGP_AJ_G0028961
protein coding gene Chr4:135458657-135465750 (-)
AKR/J MGP_AKRJ_G0028913
protein coding gene Chr4:139334728-139342025 (-)
BALB/cJ MGP_BALBcJ_G0028985
protein coding gene Chr4:136133868-136141069 (-)
C3H/HeJ MGP_C3HHeJ_G0028699
protein coding gene Chr4:139708952-139717216 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029426
protein coding gene Chr4:146536055-146543148 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026697
protein coding gene Chr4:128439951-128447123 (-)
CAST/EiJ MGP_CASTEiJ_G0028131
protein coding gene Chr4:137878295-137885380 (-)
CBA/J MGP_CBAJ_G0028664
protein coding gene Chr4:150754835-150765573 (-)
DBA/2J MGP_DBA2J_G0028813
protein coding gene Chr4:135841871-135849074 (-)
FVB/NJ MGP_FVBNJ_G0028780
protein coding gene Chr4:134868481-134876205 (-)
LP/J MGP_LPJ_G0028912
protein coding gene Chr4:141610102-141617195 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028806
protein coding gene Chr4:154718175-154725268 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029464
protein coding gene Chr4:139866916-139874009 (-)
PWK/PhJ MGP_PWKPhJ_G0027852
protein coding gene Chr4:132699235-132706480 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027677
protein coding gene Chr4:135619295-135626390 (-)
WSB/EiJ MGP_WSBEiJ_G0028209
protein coding gene Chr4:140103812-140111981 (-)



Homology
more
  • Human Ortholog
    PLA2G2F, phospholipase A2 group IIF
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PLA2G2F, phospholipase A2 group IIF
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GIIFsPLA2, sPLA2-IIF
  • Links
    NCBI Gene ID: 64600
    neXtProt AC: NX_Q9BZM2
    UniProt: Q9BZM2

  • Chr Location
    1p36.12; chr1:20139326-20150386 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Mice homozygous for a knock-out allele exhibit normal IgE antigen-dependent passive cutaneous anaphylaxis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26971 NCBI Gene Model | MGI Sequence Detail 7066 C57BL/6J ±  kb
transcript NM_001360875 RefSeq | MGI Sequence Detail 2437 C57BL/6  
polypeptide Q9QZT4 UniProt | EBI | MGI Sequence Detail 168 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 33
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:58155 Valentin E, et al., On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes. J Biol Chem. 1999 Oct 29;274(44):31195-202
  • Latest
    J:235448 Miki Y, et al., Dual Roles of Group IID Phospholipase A2 in Inflammation and Cancer. J Biol Chem. 2016 Jul 22;291(30):15588-601

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory