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Pla2g2e Gene Detail
Summary
  • Symbol
    Pla2g2e
  • Name
    phospholipase A2, group IIE
  • Synonyms
    mGIIEsPLA2s
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349660
    NCBI Gene: 26970
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:138877942-138882817 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 70.57 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349660
protein coding gene Chr4:138877911-138882817 (.)
129S1/SvImJ MGP_129S1SvImJ_G0029006
protein coding gene Chr4:141671772-141676647 (+)
A/J MGP_AJ_G0028965
protein coding gene Chr4:135589428-135594303 (+)
AKR/J MGP_AKRJ_G0028917
protein coding gene Chr4:139465878-139470673 (+)
BALB/cJ MGP_BALBcJ_G0028989
protein coding gene Chr4:136264365-136269159 (+)
C3H/HeJ MGP_C3HHeJ_G0028703
protein coding gene Chr4:139841334-139846136 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029430
protein coding gene Chr4:146696493-146701368 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026701
protein coding gene Chr4:128564823-128569718 (+)
CAST/EiJ MGP_CASTEiJ_G0028134
protein coding gene Chr4:138005497-138021269 (+)
CBA/J MGP_CBAJ_G0034166
protein coding gene Chr9:29965100-29969931 (+)
DBA/2J MGP_DBA2J_G0028817
protein coding gene Chr4:135971861-135976655 (+)
FVB/NJ MGP_FVBNJ_G0028784
protein coding gene Chr4:135001856-135006651 (+)
LP/J MGP_LPJ_G0028916
protein coding gene Chr4:141753764-141758639 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028810
protein coding gene Chr4:154855547-154860422 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029468
protein coding gene Chr4:140002950-140007825 (+)
PWK/PhJ MGP_PWKPhJ_G0027856
protein coding gene Chr4:132833616-132838448 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027681
protein coding gene Chr4:135759497-135764367 (+)
WSB/EiJ MGP_WSBEiJ_G0028213
protein coding gene Chr4:140240362-140245215 (+)



Homology
more
  • Human Ortholog
    PLA2G2E, phospholipase A2 group IIE
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PLA2G2E, phospholipase A2 group IIE
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GIIE sPLA2, sPLA2-IIE
  • Links
    NCBI Gene ID: 30814
    neXtProt AC: NX_Q9NZK7
    UniProt: Q9NZK7

  • Chr Location
    1p36.13; chr1:19920307-19923617 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Mice homozygous for a knock-out allele exhibit normal IgE antigen-dependent passive cutaneous anaphylaxis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028751 Ensembl Gene Model | MGI Sequence Detail 4876 C57BL/6J ±  kb
transcript ENSMUST00000030531 Ensembl | MGI Sequence Detail 854 Not Applicable  
polypeptide ENSMUSP00000030531 Ensembl | MGI Sequence Detail 142 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 5
    Primer pair 1
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 41
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 15
  • Earliest
    J:46940 Zambrowicz BP, et al., Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature. 1998 Apr 9;392(6676):608-11
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory