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Islr Gene Detail
Summary
  • Symbol
    Islr
  • Name
    immunoglobulin superfamily containing leucine-rich repeat
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349645
    NCBI Gene: 26968
Location & Maps
more
  • Sequence Map
    Chr9:58156265-58159221 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2957 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 31.63 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ISLR, immunoglobulin superfamily containing leucine rich repeat
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ISLR, immunoglobulin superfamily containing leucine rich repeat
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HsT17563, Meflin
  • Links
    NCBI Gene ID: 3671
    neXtProt AC: NX_O14498

  • Chr Location
    15q24.1; chr15:74173746-74176871 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037206 Ensembl Gene Model | MGI Sequence Detail 2957 C57BL/6J ±  kb
transcript ENSMUST00000041477 Ensembl | MGI Sequence Detail 2226 Not Applicable  
polypeptide ENSMUSP00000045142 Ensembl | MGI Sequence Detail 428 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    11 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 83
    cDNA 80
    Primer pair 1
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143325
References
more
  • Summaries
    All 27
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:58085 Nagasawa A, et al., Human and mouse ISLR (immunoglobulin superfamily containing leucine-rich repeat) genes: genomic structure and tissue expression. Genomics. 1999 Oct 1;61(1):37-43
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory