Sec23a
Gene Detail

Symbol Name ID

Sec23a SEC23A (S. cerevisiae) MGI:1349635

Synonyms

Msec23, Sec23r

Feature Type

protein coding gene

Genetic Map

Chromosome 12

25.97 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr12:58958383-59012017 bp, - strand From VEGA annotation of GRCm38   53635 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4642  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: SEC23 protein
Gene Tree: Sec23a

Human homologs

Human Homolog		SEC23A, Sec23 homolog A (S. cerevisiae)
NCBI Gene ID		10484
neXtProt AC		NX_Q15436
Human Synonyms		CLSD
Human Chr (Location)		14q21.1; chr14:39501123-39572437 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SEC23A

Alleles and phenotypes

All alleles(19) : Targeted(2) Gene trapped(17)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	ER to Golgi vesicle-mediated transport, intracellular protein transport, ...
Component	COPII vesicle coat, endoplasmic reticulum, ...
Function	protein binding, zinc ion binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (100)    Tissues (35)    Images (35)
Theiler Stages: 19, 23, 28

Assay Type	Results
RNA in situ	100

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000026430 (Evidence)
Ensembl Gene Model	ENSMUSG00000020986 (Evidence)
Entrez Gene	20334 (Evidence)
DoTS	DT.99857102
NIA Mouse Gene Index	U033984
Consensus CDS Project	CCDS25931.1
International Mouse Knockout Project Status	Sec23a

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026430	VEGA Gene Model | MGI Sequence Detail	53635	C57BL/6J
transcript	OTTMUST00000065364	VEGA | MGI Sequence Detail	4109	Not Applicable
polypeptide	OTTMUSP00000032571	VEGA | MGI Sequence Detail	765	Not Applicable

All sequences(31) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(157 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007123	Gelsolin domain
InterPro	IPR012990	Sec23/Sec24 beta-sandwich
InterPro	IPR006900	Sec23/Sec24, helical domain
InterPro	IPR006896	Sec23/Sec24, trunk domain
InterPro	IPR006895	Zinc finger, Sec23/Sec24-type
Protein Ontology	PR:000014586	protein transport protein Sec23A

References

(Earliest) J:3745 Carding SR, et al., Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia. J Exp Med. 1993 Feb 1;177(2):475-82
(Latest) J:186391 Tao J, et al., SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):E2001-9
All references(38)

Other accession IDs

MGD-MRK-14354, MGI:98275