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Sec23a
Gene Detail
 Symbol
Name
ID
Sec23a
SEC23A (S. cerevisiae)
MGI:1349635
Synonyms Msec23, Sec23r
Feature Type protein coding gene
Genetic Map
Chromosome 12
25.97 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr12:58958383-59012017 bp, - strand
From VEGA annotation of GRCm38

  53635 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4642  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: SEC23 protein
Gene Tree: Sec23a

Human
homologs
Human Homolog SEC23A, Sec23 homolog A (S. cerevisiae)
NCBI Gene ID 10484
neXtProt AC  NX_Q15436
Human Synonyms  CLSD
Human Chr (Location)  14q21.1; chr14:39031919-39103243 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SEC23A
Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(17) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sec23a interacts with 275 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process ER to Golgi vesicle-mediated transport, intracellular protein transport, ...
Component cell, COPII vesicle coat, ...
Function protein binding, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (100)    Tissues (35)    Images (35)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 100
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000026430 (Evidence)
Ensembl Gene ModelENSMUSG00000020986 (Evidence)
Entrez Gene20334 (Evidence)
DoTSDT.99857102
NIA Mouse Gene IndexU033984
Consensus CDS ProjectCCDS25931.1
International Mouse Knockout Project StatusSec23a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026430 VEGA Gene Model | MGI Sequence Detail 53635 C57BL/6J ±  kb
transcript OTTMUST00000065364 VEGA | MGI Sequence Detail 4109 Not Applicable 
polypeptide OTTMUSP00000032571 VEGA | MGI Sequence Detail 765 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(610 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007123 Gelsolin domain
InterPro IPR012990 Sec23/Sec24 beta-sandwich
InterPro IPR006900 Sec23/Sec24, helical domain
InterPro IPR006896 Sec23/Sec24, trunk domain
InterPro IPR002035 von Willebrand factor, type A
InterPro IPR006895 Zinc finger, Sec23/Sec24-type
Protein Ontology PR:000014586 protein transport protein Sec23A
References (Earliest) J:3745 Carding SR, et al., Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia. J Exp Med. 1993 Feb 1;177(2):475-82
(Latest) J:186391 Tao J, et al., SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):E2001-9
All references(40)
Other
accession IDs
MGD-MRK-14354, MGI:98275

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory