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Scamp1
Gene Detail
Symbol

Name
ID
Scamp1
secretory carrier membrane protein 1
MGI:1349480
Synonyms
4930505M11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 13
49.22 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr13:94201310-94285857 bp, - strand
From VEGA annotation of GRCm38

  84548 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37975  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Scamp1

Human
homologs
Human Homolog SCAMP1, secretory carrier membrane protein 1
NCBI Gene ID 9522
neXtProt AC  NX_O15126
Human Synonyms  SCAMP, SCAMP37
Human Chr (Location)  5q14.1; chr5:78360515-78480739 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted null mutation do not exhibit any overt abnormalities, but final cell capacitance of mast cells completing exocytosis was smaller than controls and an increased proportion of reversible fusion events was noted.
 
Interactions
Scamp1 interacts with 329 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process endocytosis, exocytosis, ...
Component cell, clathrin-coated vesicle, ...
Function protein binding, protein domain specific binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (12)    Tissues (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 12
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000033839 (Evidence)
Ensembl Gene ModelENSMUSG00000021687 (Evidence)
Entrez Gene107767 (Evidence)
DFCITC1626100, TC1613437, TC1583395, TC1631820
DoTSDT.101265220, DT.40147157, DT.101375075, DT.99860292, DT.99860061
NIA Mouse Gene IndexU035043
Consensus CDS ProjectCCDS36750.1
International Mouse Knockout Project StatusScamp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033839 VEGA Gene Model | MGI Sequence Detail 84548 C57BL/6J ±  kb
transcript OTTMUST00000085257 VEGA | MGI Sequence Detail 4259 Not Applicable 
polypeptide OTTMUSP00000046039 VEGA | MGI Sequence Detail 338 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(6) UniProt(13)
Polymorphisms
SNPs within 2kb(400 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007273 SCAMP
Protein Ontology PR:000014483 secretory carrier-associated membrane protein 1
References
(Earliest) J:58332 Fernandez-Chacon R, et al., Analysis of SCAMP1 function in secretory vesicle exocytosis by means of gene targeting in mice. J Biol Chem. 1999 Nov 12;274(46):32551-4
(Latest) J:140969 Felkl M, et al., Interaction assays in yeast and cultured cells confirm known and identify novel partners of the synaptic vesicle protein synaptophysin. Neuroscience. 2008 Oct 2;156(2):344-52
All references(36)
Other
accession IDs
MGI:1922292, MGI:2145229, MGI:2145416

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory