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Zw10 Gene Detail
Summary
  • Symbol
    Zw10
  • Name
    zw10 kinetochore protein
  • Synonyms
    6330566F14Rik, MmZw10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349478
    NCBI Gene: 26951
  • Gene Overview
    MyGene.info: ZW10
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:49055613-49078775 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 26.58 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    167 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349478
protein coding gene Chr9:49055581-49078775 (.)
129S1/SvImJ MGP_129S1SvImJ_G0034768
protein coding gene Chr9:47870123-47897952 (+)
A/J MGP_AJ_G0034749
protein coding gene Chr9:46441665-46466619 (+)
AKR/J MGP_AKRJ_G0034677
protein coding gene Chr9:47411907-47435103 (+)
BALB/cJ MGP_BALBcJ_G0034741
protein coding gene Chr9:46162829-46185490 (+)
C3H/HeJ MGP_C3HHeJ_G0034451
protein coding gene Chr9:47864297-47890771 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035261
protein coding gene Chr9:49226894-49255218 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032174
protein coding gene Chr9:45928128-45951896 (+)
CAST/EiJ MGP_CASTEiJ_G0033773
protein coding gene Chr9:47812272-47838497 (+)
CBA/J MGP_CBAJ_G0034423
protein coding gene Chr9:50975732-51004237 (+)
DBA/2J MGP_DBA2J_G0034582
protein coding gene Chr9:46296526-46318764 (+)
FVB/NJ MGP_FVBNJ_G0034523
protein coding gene Chr9:45544797-45568030 (+)
LP/J MGP_LPJ_G0034663
protein coding gene Chr9:48237815-48261746 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034567
protein coding gene Chr9:52658592-52682826 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035282
protein coding gene Chr9:47352850-47382565 (+)
PWK/PhJ MGP_PWKPhJ_G0033478
protein coding gene Chr9:46263350-46286997 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033313
protein coding gene Chr9:47665132-47693159 (+)
WSB/EiJ MGP_WSBEiJ_G0033886
protein coding gene Chr9:47385774-47412173 (+)



Homology
more
  • Human Ortholog
    ZW10, zw10 kinetochore protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZW10, zw10 kinetochore protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HZW10, KNTC1AP
  • Links
    NCBI Gene ID: 9183
    neXtProt AC: NX_O43264
    UniProt: O43264

  • Chr Location
    11q23.2; chr11:113733183-113773763 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 37959
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ZW10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032264 Ensembl Gene Model | MGI Sequence Detail 23163 C57BL/6J ±  kb
transcript ENSMUST00000034803 Ensembl | MGI Sequence Detail 2863 Not Applicable  
polypeptide ENSMUSP00000034803 Ensembl | MGI Sequence Detail 779 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    cDNA 67

    Microarray probesets 4
Other
Accession IDs
less
MGI:1923439
References
more
  • Summaries
    All 27
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:51740 Starr DA, et al., Conservation of the centromere/kinetochore protein ZW10. J Cell Biol. 1997 Sep 22;138(6):1289-301
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory