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Zw10 Gene Detail
Summary
  • Symbol
    Zw10
  • Name
    zw10 kinetochore protein
  • Synonyms
    6330566F14Rik, MmZw10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349478
    NCBI Gene: 26951
  • Gene Overview
    MyGene.info: ZW10
Location & Maps
more
  • Sequence Map
    Chr9:49055581-49078772 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23192 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 26.58 cM, cytoband B
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ZW10, zw10 kinetochore protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZW10, zw10 kinetochore protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HZW10, KNTC1AP
  • Links
    NCBI Gene ID: 9183
    neXtProt AC: NX_O43264

  • Chr Location
    11q23.2; chr11:113733183-113773763 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 37959
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: ZW10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032264 Ensembl Gene Model | MGI Sequence Detail 23192 C57BL/6J ±  kb
transcript ENSMUST00000034803 Ensembl | MGI Sequence Detail 2895 Not Applicable  
polypeptide ENSMUSP00000034803 Ensembl | MGI Sequence Detail 779 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    167 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000018235 centromere/kinetochore protein zw10
  • InterPro Domains
    IPR009361 RZZ complex, subunit Zw10
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 4
Other
Accession IDs
less
MGI:1923439
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:51740 Starr DA, et al., Conservation of the centromere/kinetochore protein ZW10. J Cell Biol. 1997 Sep 22;138(6):1289-301
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory