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Trpc7
Gene Detail
 Symbol
Name
ID
Trpc7
transient receptor potential cation channel, subfamily C, member 7
MGI:1349470
Synonyms TRP7, Trrp8
Feature Type protein coding gene
Genetic Map
Chromosome 13
30.27 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:56773113-56895789 bp, - strand
From VEGA annotation of GRCm38

  122677 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22689  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: transient receptor potential cation channel, subfamily C
Gene Tree: Trpc7

Human
homologs
Human Homolog TRPC7, transient receptor potential cation channel, subfamily C, member 7
NCBI Gene ID 57113
neXtProt AC  NX_Q9HCX4
Human Synonyms  TRP7
Human Chr (Location)  5q31.1; chr5:136212770-136365476 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Mice homozygous for a knock-out allele exhibit abnormal eye physiology.
 
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process calcium ion transmembrane transport, calcium ion transport, ...
Component cis-Golgi network, integral component of membrane, ...
Function calcium channel activity, ion channel activity
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (80)    Tissues (62)    Images (6)
Theiler Stages: 17, 19, 20, 22, 25, 26, 28
Assay TypeResults
RNA in situ 51
RT-PCR 29
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(9) cDNA(6) Primer pair(3)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000024552 (Evidence)
Ensembl Gene ModelENSMUSG00000021541 (Evidence)
Entrez Gene26946 (Evidence)
UniGene62409
DFCITC1591010
DoTSDT.110977707, DT.55244871
NIA Mouse Gene IndexU034835
Consensus CDS ProjectCCDS26566.1
International Mouse Knockout Project StatusTrpc7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024552 VEGA Gene Model | MGI Sequence Detail 122677 C57BL/6J ±  kb
transcript OTTMUST00000060302 VEGA | MGI Sequence Detail 3483 Not Applicable 
polypeptide OTTMUSP00000029406 VEGA | MGI Sequence Detail 862 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(12) UniProt(10)
Polymorphisms SNPs within 2kb(1462 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1466)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
InterPro IPR005821 Ion transport domain
InterPro IPR013555 Transient receptor ion channel domain
InterPro IPR004729 Transient receptor potential channel
InterPro IPR002153 Transient receptor potential channel, canonical
InterPro IPR005463 Transient receptor potential channel, canonical 7
Protein Ontology PR:000001080 transient receptor potential cation channel TRPC7
References (Earliest) J:57770 Okada T, et al., Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor. J Biol Chem. 1999 Sep 24;274(39):27359-70
(Latest) J:176849 Perez-Leighton CE, et al., Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits. Eur J Neurosci. 2011 Mar;33(5):856-67
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory