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Trpc7 Gene Detail
Summary
  • Symbol
    Trpc7
  • Name
    transient receptor potential cation channel, subfamily C, member 7
  • Synonyms
    TRP7, Trrp8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349470
    NCBI Gene: 26946
  • Gene Overview
    MyGene.info: TRPC7
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:56773113-56895993 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 30.27 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1455 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349470
protein coding gene Chr13:56773098-56895993 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020624
protein coding gene Chr13:56343255-56470445 (-)
A/J MGP_AJ_G0020578
protein coding gene Chr13:54238703-54361562 (-)
AKR/J MGP_AKRJ_G0020556
protein coding gene Chr13:55837594-55961078 (-)
BALB/cJ MGP_BALBcJ_G0020574
protein coding gene Chr13:54477039-54601167 (-)
C3H/HeJ MGP_C3HHeJ_G0020373
protein coding gene Chr13:55658283-55783369 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021008
protein coding gene Chr13:58039977-58172326 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018590
protein coding gene Chr13:52188411-52309402 (-)
CAST/EiJ MGP_CASTEiJ_G0019887
protein coding gene Chr13:55784501-55908500 (-)
CBA/J MGP_CBAJ_G0020333
protein coding gene Chr13:60261342-60390867 (-)
DBA/2J MGP_DBA2J_G0020456
protein coding gene Chr13:53786027-53908494 (-)
FVB/NJ MGP_FVBNJ_G0020435
protein coding gene Chr13:53263020-53393878 (-)
LP/J MGP_LPJ_G0020532
protein coding gene Chr13:56589179-56718765 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020464
protein coding gene Chr13:59654346-59793327 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021051
protein coding gene Chr13:55443559-55575201 (-)
PWK/PhJ MGP_PWKPhJ_G0019643
protein coding gene Chr13:53834947-53959804 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019470
protein coding gene Chr13:54389195-54514108 (-)
WSB/EiJ MGP_WSBEiJ_G0019949
protein coding gene Chr13:55812980-55939236 (-)



Homology
more
  • Human Ortholog
    TRPC7, transient receptor potential cation channel subfamily C member 7
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TRPC7, transient receptor potential cation channel subfamily C member 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    TRP7
  • Links
    NCBI Gene ID: 57113
    neXtProt AC: NX_Q9HCX4
    UniProt: Q9HCX4

  • Chr Location
    5q31.1; chr5:136213311-136365476 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal eye physiology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021541 Ensembl Gene Model | MGI Sequence Detail 122881 C57BL/6J ±  kb
    transcript ENSMUST00000022023 Ensembl | MGI Sequence Detail 3483 Not Applicable  
    polypeptide ENSMUSP00000022023 Ensembl | MGI Sequence Detail 862 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 7
      Primer pair 3

      Microarray probesets 2
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 6
      Gene Ontology 6
      Phenotypes 12
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:242282 He X, et al., Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries. Proc Natl Acad Sci U S A. 2017 Jun 06;114(23):E4582-E4591

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/27/2018
    MGI 6.13
    The Jackson Laboratory