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Polr3e Gene Detail
Summary
  • Symbol
    Polr3e
  • Name
    polymerase (RNA) III (DNA directed) polypeptide E
  • Synonyms
    RPC5, Sin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349452
    NCBI Gene: 26939
  • Gene Overview
    MyGene.info: POLR3E
Location & Maps
more
  • Sequence Map
    Chr7:120917744-120947432 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      29689 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 65.01 cM, cytoband F3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    POLR3E, RNA polymerase III subunit E
  • Vertebrate Orthologs
    10
  • Human Ortholog
    POLR3E, RNA polymerase III subunit E
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RPC5, SIN
  • Links
    NCBI Gene ID: 55718
    neXtProt AC: NX_Q9NVU0

  • Chr Location
    16p12.2; chr16:22297366-22335103 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    23
  • Gene trapped
    22
  • Targeted
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000059323 VEGA Gene Model | MGI Sequence Detail 29689 C57BL/6J ±  kb
transcript OTTMUST00000145615 VEGA | MGI Sequence Detail 3001 Not Applicable  
polypeptide OTTMUSP00000075862 VEGA | MGI Sequence Detail 710 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    134 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013004 DNA-directed RNA polymerase III subunit RPC5
  • InterPro Domains
    IPR006886 DNA-directed RNA polymerase III subunit Rpc5
Molecular
Reagents
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  • All nucleic 60
    cDNA 60

    Microarray probesets 6
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:57768 Dong Z, et al., SIN, a novel Drosophila protein that associates with the RNA binding protein sex-lethal. Gene. 1999 Sep 17;237(2):421-8
  • Latest
    J:213067 Riccomagno MM, et al., Cas adaptor proteins organize the retinal ganglion cell layer downstream of integrin signaling. Neuron. 2014 Feb 19;81(4):779-86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory