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Cenph Gene Detail
Summary
  • Symbol
    Cenph
  • Name
    centromere protein H
  • Synonyms
    1700021I11Rik, 2410018A12Rik, 2610042E16Rik, 2810046K12Rik, CENP-H, ENP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349448
    NCBI Gene: 26886
  • Gene Overview
    MyGene.info: CENPH
Location & Maps
more
  • Sequence Map
    Chr13:100759674-100775899 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16226 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CENPH, centromere protein H
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CENPH, centromere protein H
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 64946
    neXtProt AC: NX_Q9H3R5

  • Chr Location
    5p15.2; chr5:69189548-69210357 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    22
  • Gene trapped
    16
  • Targeted
    6
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033835 VEGA Gene Model | MGI Sequence Detail 16226 C57BL/6J ±  kb
transcript OTTMUST00000085245 VEGA | MGI Sequence Detail 1251 Not Applicable  
polypeptide OTTMUSP00000046031 VEGA | MGI Sequence Detail 241 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    106 from dbSNP Build 142
  • PCR
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005328 centromere protein H
  • InterPro Domains
    IPR008426 Centromere protein H
Molecular
Reagents
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  • All nucleic 44
    cDNA 42
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
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MGI:1915102, MGI:1917572, MGI:1919934, MGI:1924184, MGI:2145375
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:57771 Sugata N, et al., Characterization of a novel kinetochore protein, CENP-H. J Biol Chem. 1999 Sep 24;274(39):27343-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory