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Haao Gene Detail
Summary
  • Symbol
    Haao
  • Name
    3-hydroxyanthranilate 3,4-dioxygenase
  • Synonyms
    0610007K21Rik, 0610012J07Rik, 3HAO, 3-HAO, 3-HAOxase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349444
    NCBI Gene: 107766
Location & Maps
more
  • Sequence Map
    Chr17:83831356-83846790 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      15435 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 54.85 cM, cytoband E4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    HAAO, 3-hydroxyanthranilate 3,4-dioxygenase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HAAO, 3-hydroxyanthranilate 3,4-dioxygenase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    3-HAO, HAO
  • Links
    NCBI Gene ID: 23498
    neXtProt AC: NX_P46952

  • Chr Location
    2p21; chr2:42767089-42793138 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    94
  • Tissues
    94
  • cDNA Data
    96
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000000673 Ensembl Gene Model | MGI Sequence Detail 15435 C57BL/6J ±  kb
transcript ENSMUST00000000687 Ensembl | MGI Sequence Detail 1222 Not Applicable  
polypeptide ENSMUSP00000000687 Ensembl | MGI Sequence Detail 286 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    251 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008427 3-hydroxyanthranilate 3,4-dioxygenase
  • EC
    1.13.11.6
  • InterPro Domains
    IPR016700 3-hydroxyanthranilate 3, 4-dioxygenase, metazoan
    IPR010329 3-hydroxyanthranilic acid dioxygenase
    IPR011051 RmlC-like cupin domain
    IPR014710 RmlC-like jelly roll fold
Molecular
Reagents
less
  • All nucleic 97
    Genomic 1
    cDNA 96

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913307, MGI:1918919
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:131587 Nakano K, et al., Abnormally high activity of 3-hydroxyanthranilate 3,4-dioxygenase in brain of epilepsy-prone El mice. Brain Res. 1992 Feb 14;572(1-2):1-4
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/13/2016
MGI 6.05 		The Jackson Laboratory