About   Help   FAQ
Ddx3y Gene Detail
Summary
  • Symbol
    Ddx3y
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
  • Synonyms
    8030469F12Rik, D1Pas1-rs1, Dby
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349406
    NCBI Gene: 26900
  • Gene Overview
    MyGene.info: DDX3Y
Location & Maps
more
  • Genetic Map
    Chromosome Y, cytoband p
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DDX3Y, DEAD-box helicase 3, Y-linked
  • Vertebrate Orthologs
    4
  • Human Ortholog
    DDX3Y, DEAD-box helicase 3, Y-linked
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DBY
  • Links
    NCBI Gene ID: 8653
    neXtProt AC: NX_O15523

  • Chr Location
    Yq11; chrY:12904108-12920478 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human DDX3Y associations

Human Disease Mouse Models
       Spermatogenic Failure, Y-Linked, 2; SPGFY2   OMIM: 415000
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    4
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045279 VEGA Gene Model | MGI Sequence Detail 25859 C57BL/6J ±  kb
transcript OTTMUST00000118924 VEGA | MGI Sequence Detail 4600 Not Applicable  
polypeptide OTTMUSP00000066311 VEGA | MGI Sequence Detail 658 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    45 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006365 ATP-dependent RNA helicase DDX3Y
  • EC
  • InterPro Domains
    IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
    IPR011545 DEAD/DEAH box helicase domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR014014 RNA helicase, DEAD-box type, Q motif
Molecular
Reagents
less
  • All nucleic 63
    Genomic 2
    cDNA 56
    Primer pair 4
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-16301, MGI:1924744, MGI:99524
References
more
  • Summaries
    All 37
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:17429 Gee SL, et al., Mouse erythroid cells express multiple putative RNA helicase genes exhibiting high sequence conservation from yeast to mammals. Gene. 1994 Mar 25;140(2):171-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory