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B3galnt1
Gene Detail
Symbol

Name
ID
B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
MGI:1349405
Synonyms
B3galt3, Brainiac 1, Globoside blood group, Mbrn 1
Feature Type
protein coding gene
Genetic Map
Chromosome 3
32.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:69574158-69598960 bp, - strand
From VEGA annotation of GRCm38

  24803 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32457  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: B3GALNT1
Gene Tree: B3galnt1

Human
homologs
B3GALNT1, beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8706
neXtProt AC: NX_O75752

Human Synonyms: B3GALT3, beta3Gal-T3, galT3, Gb4Cer, GLCT3, GLOB, P, P1

Human Chr (Location): 3q25; chr3:161083883-161105630 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(4) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
A homozygous null mutation of this gene results in embryonic lethality. Mice homozygous for a second allele appear normal.
 
Interactions
B3galnt1 interacts with 163 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Expression
Literature Summary: (5 records)
Data Summary: Results (204)    Tissues (140)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 166
RT-PCR 38
cDNA source data(30)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(31) cDNA(30) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000051643 (Evidence)
Ensembl Gene Model ENSMUSG00000043300 (Evidence)
Entrez Gene 26879 (Evidence)
UniGene 153710
DFCI TC1580894, TC1679826
DoTS DT.40180969
NIA Mouse Gene Index U024144
EC 2.4.1.79
Consensus CDS Project CCDS17406.1
International Mouse Phenotyping Consortium Status B3galnt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051643 VEGA Gene Model | MGI Sequence Detail 24803 C57BL/6J ±  kb
transcript OTTMUST00000130307 VEGA | MGI Sequence Detail 2028 Not Applicable 
polypeptide OTTMUSP00000069864 VEGA | MGI Sequence Detail 331 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(126 from dbSNP Build 137)    SNPs within 2kb including multiple locations(130)
Protein-related
information
ResourceIDDescription
InterPro IPR002659 Glycosyl transferase, family 31
Protein Ontology PR:000004581 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
References
(Earliest) J:45045 Hennet T, et al., Genomic cloning and expression of three murine UDP-galactose: beta-N-acetylglucosamine beta1,3-galactosyltransferase genes. J Biol Chem. 1998 Jan 2;273(1):58-65
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory