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B3galnt1
Gene Detail
 Symbol
Name
ID
B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
MGI:1349405
Synonyms B3galt3, Brainiac 1, Globoside blood group, Mbrn 1
Feature Type protein coding gene
Genetic Map
Chromosome 3
32.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:69574186-69598861 bp, - strand
From NCBI annotation of GRCm38

  24676 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32457  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: B3galnt1

Human
homologs
Human Homolog B3GALNT1, beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
NCBI Gene ID 8706
neXtProt AC  NX_O75752
Human Synonyms  B3GALT3, beta3Gal-T3, galT3, Gb4Cer, GLCT3, GLOB, P, P1
Human Chr (Location)  3q25; chr3:161083883-161105372 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(4) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
A homozygous null mutation of this gene results in embryonic lethality. Mice homozygous for a second allele appear normal.
 
Interactions
B3galnt1 interacts with 163 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process oligosaccharide biosynthetic process, protein glycosylation
Component Golgi apparatus, integral component of membrane, ...
Function galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity, galactosyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (204)    Tissues (140)    Images (32)
Theiler Stages: 22, 23, 28
Assay TypeResults
RNA in situ 166
RT-PCR 38
cDNA source data(30)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(31) cDNA(30) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000043300 (Evidence)
Entrez Gene26879 (Evidence)
UniGene153710
DFCITC1580894, TC1679826
DoTSDT.40180969
NIA Mouse Gene IndexU024144
EC2.4.1.79
Consensus CDS ProjectCCDS17406.1
International Mouse Knockout Project StatusB3galnt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 26879 NCBI Gene Model | MGI Sequence Detail 24676 C57BL/6J ±  kb
transcript NM_020026 RefSeq | MGI Sequence Detail 2283 C57BL/6 
polypeptide Q920V1 UniProt | EBI | MGI Sequence Detail 331 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(126 from dbSNP Build 137)    SNPs within 2kb including multiple locations(130)
Protein-related
information
ResourceIDDescription
InterPro IPR002659 Glycosyl transferase, family 31
Protein Ontology PR:000004581 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
Graphical View of Protein Domain Structure
References (Earliest) J:45045 Hennet T, et al., Genomic cloning and expression of three murine UDP-galactose: beta-N-acetylglucosamine beta1,3-galactosyltransferase genes. J Biol Chem. 1998 Jan 2;273(1):58-65
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory