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Polr2f Gene Detail
Summary
  • Symbol
    Polr2f
  • Name
    polymerase (RNA) II (DNA directed) polypeptide F
  • Synonyms
    1810060D16Rik, RNA Pol II
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349393
    NCBI Gene: 69833
  • Gene Overview
    MyGene.info: POLR2F
Location & Maps
more
  • Sequence Map
    Chr15:79141367-79151767 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10401 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    POLR2F, RNA polymerase II subunit F
  • Vertebrate Orthologs
    10
  • Human Ortholog
    POLR2F, RNA polymerase II subunit F
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HRBP14.4, POLRF, RPABC14.4, RPABC2, RPB14.4, RPB6, RPC15
  • Links
    NCBI Gene ID: 5435
    neXtProt AC: NX_P61218

  • Chr Location
    22q13.1; chr22:37953663-38041915 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    30 phenotype references
  • All Mutations and Alleles
    29
  • Chemically induced (other)
    1
  • Gene trapped
    23
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Polr2f
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69833 NCBI Gene Model | MGI Sequence Detail 10401 C57BL/6J ±  kb
transcript NM_027231 RefSeq | MGI Sequence Detail 579 Not Specified  
polypeptide P61219 UniProt | EBI | MGI Sequence Detail 127 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    127 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012992 DNA-directed RNA polymerases I, II, and III subunit RPABC2
  • InterPro Domains
    IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit
    IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site
    IPR028363 DNA-directed RNA polymerase, subunit RPB6
    IPR006110 RNA polymerase, subunit omega/K/RPB6
    IPR012293 RNA polymerase subunit, RPB6/omega
Molecular
Reagents
less
  • All nucleic 62
    cDNA 62

    Microarray probesets 5
Other
Accession IDs
less
MGI:1917083
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 4
    Phenotypes 30
  • Earliest
    J:56036 Southard-Smith EM, et al., Comparative analyses of the Dominant megacolon-SOX10 genomic interval in mouse and human. Mamm Genome. 1999 Jul;10(7):744-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory