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Tpsg1
Gene Detail
 Symbol
Name
ID
Tpsg1
tryptase gamma 1
MGI:1349391
Synonyms Prss31, TMT
Feature Type protein coding gene
Genetic Map
Chromosome 17
12.53 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr17:25369273-25374442 bp, + strand
From VEGA annotation of GRCm38

  5170 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74994  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Tpsg1

Human
homologs
Human Homolog TPSG1, tryptase gamma 1
NCBI Gene ID 25823
neXtProt AC  NX_Q9NRR2
Human Synonyms  PRSS31, TMT, trpA
Human Chr (Location)  16p13.3; chr16:1221488-1225254 (-)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process proteolysis
Component integral component of membrane, membrane
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(13) Genomic(1) cDNA(11) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000034504 (Evidence)
Ensembl Gene ModelENSMUSG00000033200 (Evidence)
Entrez Gene26945 (Evidence)
UniGene180108
DFCITC1586939, TC1612615
NIA Mouse Gene IndexU017674
EC3.4.21.-
Consensus CDS ProjectCCDS28518.1
International Mouse Knockout Project StatusTpsg1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034504 VEGA Gene Model | MGI Sequence Detail 5170 C57BL/6J ±  kb
transcript OTTMUST00000087544 VEGA | MGI Sequence Detail 1186 Not Applicable 
polypeptide OTTMUSP00000047612 VEGA | MGI Sequence Detail 311 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(16) UniProt(6)
Polymorphisms SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000016593 tryptase gamma
References (Earliest) J:58140 Wong GW, et al., Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COOH-terminal hydrophobic extension. J Biol Chem. 1999 Oct 22;274(43):30784-93
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory