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Cops7b Gene Detail
Summary
  • Symbol
    Cops7b
  • Name
    COP9 signalosome subunit 7B
  • Synonyms
    COP9 complex S7b, D1Wsu66e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349388
    NCBI Gene: 26895
  • Gene Overview
    MyGene.info: COPS7B
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:86582892-86606500 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 43.97 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349388
protein coding gene Chr1:86582892-86609375 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016251
protein coding gene Chr1:87873370-87907219 (+)
A/J MGP_AJ_G0016232
protein coding gene Chr1:84602218-84629796 (+)
AKR/J MGP_AKRJ_G0016193
protein coding gene Chr1:87080797-87107212 (+)
BALB/cJ MGP_BALBcJ_G0016189
protein coding gene Chr1:84717780-84744939 (+)
C3H/HeJ MGP_C3HHeJ_G0016017
protein coding gene Chr1:87323590-87356241 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016645
protein coding gene Chr1:91206345-91234060 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014367
protein coding gene Chr1:79085596-79113954 (+)
CAST/EiJ MGP_CASTEiJ_G0015602
protein coding gene Chr1:86555241-86581102 (+)
CBA/J MGP_CBAJ_G0015993
protein coding gene Chr1:94048546-94077031 (+)
DBA/2J MGP_DBA2J_G0016096
protein coding gene Chr1:83911419-83938334 (+)
FVB/NJ MGP_FVBNJ_G0016095
protein coding gene Chr1:82965772-82992595 (+)
LP/J MGP_LPJ_G0016167
protein coding gene Chr1:88962962-88995553 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016121
protein coding gene Chr1:97297219-97324556 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016688
protein coding gene Chr1:87203969-87234176 (+)
PWK/PhJ MGP_PWKPhJ_G0015389
protein coding gene Chr1:83196964-83225445 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015169
protein coding gene Chr1:86148973-86176960 (+)
WSB/EiJ MGP_WSBEiJ_G0015666
protein coding gene Chr1:86845649-86873330 (+)



Homology
more
  • Human Ortholog
    COPS7B, COP9 signalosome subunit 7B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    COPS7B, COP9 signalosome subunit 7B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CSN7B, SGN7b
  • Links
    NCBI Gene ID: 64708
    neXtProt AC: NX_Q9H9Q2
    UniProt: Q9H9Q2

  • Chr Location
    2q37.1; chr2:231781671-231809253 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26895 NCBI Gene Model | MGI Sequence Detail 23609 C57BL/6J ±  kb
transcript NM_172974 RefSeq | MGI Sequence Detail 2819 C57BL/6  
polypeptide Q8BV13 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR027530 COP9 signalosome complex subunit 7b
    IPR000717 Proteasome component (PCI) domain
Molecular
Reagents
less
  • All nucleic 64
    cDNA 63
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-34265, MGI:106571
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory