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Cops7b Gene Detail
Summary
  • Symbol
    Cops7b
  • Name
    COP9 signalosome subunit 7B
  • Synonyms
    COP9 complex S7b, D1Wsu66e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349388
    NCBI Gene: 26895
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:86510363-86534550 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 43.97 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349388
 protein coding gene Chr1:86510363-86537097 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016251
 protein coding gene Chr1:87873370-87907219 (+)
A/J MGP_AJ_G0016232
 protein coding gene Chr1:84602218-84629796 (+)
AKR/J MGP_AKRJ_G0016193
 protein coding gene Chr1:87080797-87107212 (+)
BALB/cJ MGP_BALBcJ_G0016189
 protein coding gene Chr1:84717780-84744939 (+)
C3H/HeJ MGP_C3HHeJ_G0016017
 protein coding gene Chr1:87323590-87356241 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016645
 protein coding gene Chr1:91206345-91234060 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014367
 protein coding gene Chr1:79085596-79113954 (+)
CAST/EiJ MGP_CASTEiJ_G0015602
 protein coding gene Chr1:86555241-86581102 (+)
CBA/J MGP_CBAJ_G0015993
 protein coding gene Chr1:94048546-94077031 (+)
DBA/2J MGP_DBA2J_G0016096
 protein coding gene Chr1:83911419-83938334 (+)
FVB/NJ MGP_FVBNJ_G0016095
 protein coding gene Chr1:82965772-82992595 (+)
LP/J MGP_LPJ_G0016167
 protein coding gene Chr1:88962962-88995553 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016121
 protein coding gene Chr1:97297219-97324556 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016688
 protein coding gene Chr1:87203969-87234176 (+)
PWK/PhJ MGP_PWKPhJ_G0015389
 protein coding gene Chr1:83196964-83225445 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015169
 protein coding gene Chr1:86148973-86176960 (+)
WSB/EiJ MGP_WSBEiJ_G0015666
 protein coding gene Chr1:86845649-86873330 (+)



Homology
more
  • Human Ortholog
    COPS7B, COP9 signalosome subunit 7B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COPS7B, COP9 signalosome subunit 7B
  • Synonyms
    CSN7B, SGN7b
  • Links
    NCBI Gene ID: 64708
    neXtProt AC: NX_Q9H9Q2
    UniProt: Q9H9Q2

  • Chr Location
    2q37.1; chr2:231781671-231809254 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    836
  • Tissues
    45
  • cDNA Data
    63
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26895 NCBI Gene Model | MGI Sequence Detail 24188 C57BL/6J ±  kb
transcript NM_172974 RefSeq | MGI Sequence Detail 2819 ZRU/MplStud  
polypeptide Q8BV13 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000005745 COP9 signalosome complex subunit 7b
    (term hierarchy)
  • InterPro Domains
    IPR041481 COP9 signalosome complex subunit 7, helix I
    IPR045237 Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7
    IPR000717 Proteasome component (PCI) domain
Molecular
Reagents
less
  • All nucleic 64
    cDNA 63
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-34265, MGI:106571
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory