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Sdc3
Gene Detail
Symbol

Name
ID
Sdc3
syndecan 3
MGI:1349163
Synonyms
MGC:65603, MGC:69616, mKIAA0468, syn-3, Synd3
Feature Type
protein coding gene
Genetic Map
Chromosome 4
63.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr4:130792537-130826319 bp, + strand
From VEGA annotation of GRCm38

  33783 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7965  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: SDC3
Protein SuperFamily: syndecan-3
Gene Tree: Sdc3

Human
homologs
SDC3, syndecan 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9672
neXtProt AC: NX_O75056

Human Synonyms: SDCN, SYND3

Human Chr (Location): 1p35.2; chr1:30869466-30909735 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SDC3

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Genomic Mutations involving Sdc3 (1)
Incidental mutations (data from APF )
 
Homozygotes for a targeted null mutation exhibit enhanced long-term potentiation and impaired hippocampus-dependent memory.
 
Interactions
Sdc3 interacts with 275 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell adhesion, cell migration, ...
Component axon, cell surface, ...
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (32)    Tissues (22)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 4
RNA in situ 26
Northern blot 1
RT-PCR 1
cDNA source data(163)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase sdc3 ; ZFIN sdc3    NEW 
Molecular
reagents
All nucleic(166) cDNA(164) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000009594 (Evidence)
Ensembl Gene Model ENSMUSG00000025743 (Evidence)
Entrez Gene 20970 (Evidence)
UniGene 206536
DFCI TC1575482, TC1597374, TC1635352
DoTS DT.101153404, DT.101393218, DT.97347619
NIA Mouse Gene Index U040628
Consensus CDS Project CCDS38894.1
International Mouse Phenotyping Consortium Status Sdc3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009594 VEGA Gene Model | MGI Sequence Detail 33783 C57BL/6J ±  kb
transcript OTTMUST00000022034 VEGA | MGI Sequence Detail 4973 Not Applicable 
polypeptide OTTMUSP00000010039 VEGA | MGI Sequence Detail 442 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(6) UniProt(2)
Polymorphisms
All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(280 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003585 Neurexin/syndecan/glycophorin C
InterPro IPR001050 Syndecan
InterPro IPR031194 Syndecan-3
InterPro IPR030479 Syndecan, conserved site
InterPro IPR027789 Syndecan/Neurexin domain
Protein Ontology PR:000001936 syndecan-3
References
(Earliest) J:31834 Sutherland AE, et al., Expression of syndecan, a putative low affinity fibroblast growth factor receptor, in the early mouse embryo. Development. 1991 Sep;113(1):339-51
(Latest) J:218062 Kim N, et al., Regulation of retinal axon growth by secreted Vax1 homeodomain protein. Elife. 2014;3:e02671
All references(64)
Other
accession IDs
MGD-MRK-14688, MGI:98465

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory