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Sdc3
Gene Detail
 Symbol
Name
ID
Sdc3
syndecan 3
MGI:1349163
Synonyms MGC:65603, MGC:69616, mKIAA0468, syn-3, Synd3
Feature Type protein coding gene
Genetic Map
Chromosome 4
63.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr4:130792537-130826319 bp, + strand
From VEGA annotation of GRCm38

  33783 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7965  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: syndecan-3
Gene Tree: Sdc3

Human
homologs
Human Homolog SDC3, syndecan 3
NCBI Gene ID 9672
neXtProt AC  NX_O75056
Human Synonyms  SDCN, SYND3
Human Chr (Location)  1p35.2; chr1:30869466-30908633 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SDC3
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Homozygotes for a targeted null mutation exhibit enhanced long-term potentiation and impaired hippocampus-dependent memory.
 
Interactions
Sdc3 interacts with 275 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process cell adhesion
Component axon, integral component of membrane, ...
Function cytoskeletal protein binding
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (30)    Tissues (21)    Images (6)
Theiler Stages: 16, 17, 22, 23, 28
Assay TypeResults
Immunohistochemistry 2
RNA in situ 26
Northern blot 1
RT-PCR 1
cDNA source data(163)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(166) cDNA(164) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000009594 (Evidence)
Ensembl Gene ModelENSMUSG00000025743 (Evidence)
Entrez Gene20970 (Evidence)
UniGene206536
DFCITC1575482, TC1597374, TC1635352
DoTSDT.101153404, DT.101393218, DT.97347619
NIA Mouse Gene IndexU040628
Consensus CDS ProjectCCDS38894.1
International Mouse Knockout Project StatusSdc3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009594 VEGA Gene Model | MGI Sequence Detail 33783 C57BL/6J ±  kb
transcript OTTMUST00000022034 VEGA | MGI Sequence Detail 4973 Not Applicable 
polypeptide OTTMUSP00000010039 VEGA | MGI Sequence Detail 442 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(14) UniProt(2)
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(280 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003585 Neurexin/syndecan/glycophorin C
InterPro IPR001050 Syndecan
Protein Ontology PR:000001936 syndecan-3
References (Earliest) J:31834 Sutherland AE, et al., Expression of syndecan, a putative low affinity fibroblast growth factor receptor, in the early mouse embryo. Development. 1991 Sep;113(1):339-51
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(64)
Other
accession IDs
MGD-MRK-14688, MGI:98465

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory