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Foxn2 Gene Detail
Summary
  • Symbol
    Foxn2
  • Name
    forkhead box N2
  • Synonyms
    3230402J05Rik, 6030465J18Rik, Fkh19, HTLF
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347478
    NCBI Gene: 14236
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:88440712-88490533 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 57.97 cM, cytoband E5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    203 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347478
protein coding gene Chr17:88440711-88490533 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024109
protein coding gene Chr17:91936712-91984554 (+)
A/J MGP_AJ_G0024069
protein coding gene Chr17:88962285-89013154 (+)
AKR/J MGP_AKRJ_G0024038
protein coding gene Chr17:90439882-90487542 (+)
BALB/cJ MGP_BALBcJ_G0024070
protein coding gene Chr17:88795555-88842554 (+)
C3H/HeJ MGP_C3HHeJ_G0023835
protein coding gene Chr17:91351271-91398401 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024515
protein coding gene Chr17:95129905-95181242 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021953
protein coding gene Chr17:84024338-84067340 (+)
CAST/EiJ MGP_CASTEiJ_G0023314
protein coding gene Chr17:92207764-92258816 (+)
CBA/J MGP_CBAJ_G0023808
protein coding gene Chr17:99159160-99206847 (+)
DBA/2J MGP_DBA2J_G0023937
protein coding gene Chr17:87352944-87400174 (+)
FVB/NJ MGP_FVBNJ_G0023903
protein coding gene Chr17:86885153-86933346 (+)
LP/J MGP_LPJ_G0024021
protein coding gene Chr17:92730049-92780409 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023931
protein coding gene Chr17:98942708-98994368 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024560
protein coding gene Chr17:91000543-91050699 (+)
PWK/PhJ MGP_PWKPhJ_G0023059
protein coding gene Chr17:87046130-87095099 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022870
protein coding gene Chr17:87753382-87797656 (+)
WSB/EiJ MGP_WSBEiJ_G0023380
protein coding gene Chr17:91853067-91901802 (+)



Homology
more
  • Human Ortholog
    FOXN2, forkhead box N2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    FOXN2, forkhead box N2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HTLF
  • Links
    NCBI Gene ID: 3344
    neXtProt AC: NX_P32314
    UniProt: P32314

  • Chr Location
    2p16.3; chr2:48314640-48379295 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 31078
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FOXN2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14236 NCBI Gene Model | MGI Sequence Detail 49822 C57BL/6J ±  kb
transcript NM_001355742 RefSeq | MGI Sequence Detail 5358 C57BL/6  
polypeptide NP_001342671 RefSeq | MGI Sequence Detail 429 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001766 Fork head domain
    IPR018122 Fork head domain conserved site1
    IPR030456 Fork head domain conserved site 2
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
less
  • All nucleic 20
    Genomic 1
    cDNA 17
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1276569, MGI:1918026, MGI:2442145
References
more
  • Summaries
    All 38
    Developmental Gene Expression 9
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:43593 Schorpp M, et al., Characterization of mouse and human nude genes. Immunogenetics. 1997;46(6):509-15
  • Latest
    J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory