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Foxj1
Gene Detail
 Symbol
Name
ID
Foxj1
forkhead box J1
MGI:1347474
Synonyms FKHL-13, Hfh4, HFH-4
Feature Type protein coding gene
Genetic Map
Chromosome 11
81.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:116330704-116335399 bp, - strand
From VEGA annotation of GRCm38

  4696 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1117  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Foxj1

Human
homologs
Human Homolog FOXJ1, forkhead box J1
NCBI Gene ID 2302
neXtProt AC  NX_Q92949
Human Synonyms  FKHL13, HFH4, HFH-4
Human Chr (Location)  17q25.1; chr17:76136333-76141299 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Animals homozygous for targeted mutations in this gene exhibit random determination of left-right asymmetry and defective ciliogenesis.
 
Human Diseases Modeled Using Mouse Foxj1 (1)    Alleles Annotated to Human Diseases(2)    Phenotype Images(4)
Interactions
Foxj1 interacts with 148 markers (Mir10b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process actin cytoskeleton organization, activation of Rho GTPase activity, ...
Component nucleus
Function DNA binding, DNA binding, bending, ...
External Resources: FuncBase
Expression
Literature Summary: (69 records)
Data Summary: Results (276)    Tissues (182)    Images (50)
Theiler Stages: 9, 10, 11, 12, 13, 14, 15, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 4
RNA in situ 241
Northern blot 11
Western blot 6
RT-PCR 14
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) Genomic(6) cDNA(20) Primer pair(4) Other(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000003841 (Evidence)
Ensembl Gene ModelENSMUSG00000034227 (Evidence)
Entrez Gene15223 (Evidence)
UniGene378938
DFCITC1584898
Consensus CDS ProjectCCDS25665.1
International Mouse Knockout Project StatusFoxj1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003841 VEGA Gene Model | MGI Sequence Detail 4696 C57BL/6J ±  kb
transcript OTTMUST00000008445 VEGA | MGI Sequence Detail 2623 Not Applicable 
polypeptide OTTMUSP00000004095 VEGA | MGI Sequence Detail 421 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(4) UniProt(2)
Polymorphisms RFLP(2) : SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001766 Transcription factor, fork head
InterPro IPR018122 Transcription factor, fork head, conserved site
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000007628 forkhead box protein J1
References (Earliest) J:20863 Clevidence DE, et al., Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family. Proc Natl Acad Sci U S A. 1993 May 1;90(9):3948-52
(Latest) J:204465 Volckaert T, et al., Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors. Development. 2013 Sep;140(18):3731-42
All references(108)
Disease annotation references (2)
Other
accession IDs
MGD-MRK-16697, MGI:99901

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory