About   Help   FAQ
Mmp23 Gene Detail
Summary
  • Symbol
    Mmp23
  • Name
    matrix metallopeptidase 23
  • Synonyms
    CA-MMP, cysteine array matrix metalloproteinase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347361
    NCBI Gene: 26561
Location & Maps
more
  • Sequence Map
    Chr4:155650655-155653384 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2730 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MMP23B, matrix metallopeptidase 23B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MMP23B, matrix metallopeptidase 23B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MIFR, MIFR-1, MMP22, MMP23A
  • Links
    NCBI Gene ID: 8510
    neXtProt AC: NX_O75900

  • Chr Location
    1p36.3; chr1:1632181-1634654 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 3424
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: MMP23B
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    3
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010727 VEGA Gene Model | MGI Sequence Detail 2730 C57BL/6J ±  kb
transcript OTTMUST00000025041 VEGA | MGI Sequence Detail 1434 Not Applicable  
polypeptide OTTMUSP00000011475 VEGA | MGI Sequence Detail 391 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    27 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 1
    cDNA 18
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:57238 Pei D, CA-MMP: a matrix metalloproteinase with a novel cysteine array, but without the classic cysteine switch. FEBS Lett. 1999 Aug 27;457(2):262-70
  • Latest
    J:213098 Tocchi A, et al., Functional interactions between matrix metalloproteinases and glycosaminoglycans. FEBS J. 2013 May;280(10):2332-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/26/2016
MGI 6.02
The Jackson Laboratory