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Mmp23
Gene Detail
 Symbol
Name
ID
Mmp23
matrix metallopeptidase 23
MGI:1347361
Synonyms CA-MMP, cysteine array matrix metalloproteinase
Feature Type protein coding gene
Genetic Map
Chromosome 4
86.85 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:155650655-155653384 bp, - strand
From VEGA annotation of GRCm38

  2730 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3424  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mmp23

Human
homologs
Human Homolog MMP23B, matrix metallopeptidase 23B
NCBI Gene ID 8510
neXtProt AC  NX_O75900
Human Synonyms  MIFR, MIFR-1, MMP22, MMP23A
Human Chr (Location)  1p36.3; chr1:1631681-1634654 (+)  GRCh38
Alleles
and
phenotypes
All alleles(7) : Gene trapped(3) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process proteolysis
Component endoplasmic reticulum, extracellular matrix, ...
Function hydrolase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (42)    Tissues (15)    Images (19)
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
RNA in situ 30
RT-PCR 12
cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(20) Genomic(1) cDNA(18) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000010727 (Evidence)
Ensembl Gene ModelENSMUSG00000029061 (Evidence)
Entrez Gene26561 (Evidence)
UniGene29373
DFCITC1582587, TC1655148
DoTSDT.530860, DT.91364402
NIA Mouse Gene IndexU025875
EC3.4.24.-
Consensus CDS ProjectCCDS19034.1
International Mouse Knockout Project StatusMmp23
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010727 VEGA Gene Model | MGI Sequence Detail 2730 C57BL/6J ±  kb
transcript OTTMUST00000025041 VEGA | MGI Sequence Detail 1434 Not Applicable 
polypeptide OTTMUSP00000011475 VEGA | MGI Sequence Detail 391 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(14) UniProt(1)
Polymorphisms SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR024079 Metallopeptidase, catalytic domain
InterPro IPR003582 Metridin-like ShK toxin
InterPro IPR021190 Peptidase M10A
InterPro IPR001818 Peptidase M10, metallopeptidase
InterPro IPR006026 Peptidase, metallopeptidase
Protein Ontology PR:000010916 matrix metalloproteinase-23
References (Earliest) J:57238 Pei D, CA-MMP: a matrix metalloproteinase with a novel cysteine array, but without the classic cysteine switch. FEBS Lett. 1999 Aug 27;457(2):262-70
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory