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Mmp23 Gene Detail
Summary
  • Symbol
    Mmp23
  • Name
    matrix metallopeptidase 23
  • Synonyms
    CA-MMP, cysteine array matrix metalloproteinase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347361
    NCBI Gene: 26561
  • Gene Overview
    MyGene.info: MMP23B
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:155650655-155653384 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 86.85 cM, cytoband E2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347361
protein coding gene Chr4:155650655-155654539 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029220
protein coding gene Chr4:160000045-160002774 (-)
A/J MGP_AJ_G0029185
protein coding gene Chr4:153272445-153275174 (-)
AKR/J MGP_AKRJ_G0029133
protein coding gene Chr4:157438374-157441103 (-)
BALB/cJ MGP_BALBcJ_G0029201
protein coding gene Chr4:153743693-153746422 (-)
C3H/HeJ MGP_C3HHeJ_G0028922
protein coding gene Chr4:157984030-157986759 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029650
protein coding gene Chr4:165682553-165685282 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026895
protein coding gene Chr4:145561821-145564543 (-)
CAST/EiJ MGP_CASTEiJ_G0028334
protein coding gene Chr4:155439792-155442511 (-)
CBA/J MGP_CBAJ_G0028884
protein coding gene Chr4:170687304-170690033 (-)
DBA/2J MGP_DBA2J_G0029033
protein coding gene Chr4:153292144-153294873 (-)
FVB/NJ MGP_FVBNJ_G0028996
protein coding gene Chr4:152531912-152534640 (-)
LP/J MGP_LPJ_G0029123
protein coding gene Chr4:159917114-159919843 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029023
protein coding gene Chr4:173499835-173502563 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029682
protein coding gene Chr4:158065134-158067863 (-)
PWK/PhJ MGP_PWKPhJ_G0028055
protein coding gene Chr4:149432440-149435166 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027889
protein coding gene Chr4:152323929-152326591 (-)
WSB/EiJ MGP_WSBEiJ_G0028414
protein coding gene Chr4:158235492-158238220 (-)



Homology
more
  • Human Ortholog
    MMP23B, matrix metallopeptidase 23B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MMP23B, matrix metallopeptidase 23B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MIFR, MIFR-1, MMP22, MMP23A
  • Links
    NCBI Gene ID: 8510
    neXtProt AC: NX_O75900
    UniProt: O75900

  • Chr Location
    1p36.33; chr1:1631681-1634654 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3424
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MMP23B
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029061 Ensembl Gene Model | MGI Sequence Detail 2730 C57BL/6J ±  kb
transcript ENSMUST00000030937 Ensembl | MGI Sequence Detail 1434 Not Applicable  
polypeptide ENSMUSP00000030937 Ensembl | MGI Sequence Detail 391 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    Genomic 1
    cDNA 19
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:57238 Pei D, CA-MMP: a matrix metalloproteinase with a novel cysteine array, but without the classic cysteine switch. FEBS Lett. 1999 Aug 27;457(2):262-70
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory