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Homer3
Gene Detail
 Symbol
Name
ID
Homer3
homer homolog 3 (Drosophila)
MGI:1347359
Feature Type protein coding gene
Genetic Map
Chromosome 8
34.15 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:70282827-70294361 bp, + strand
From VEGA annotation of GRCm38

  11535 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37972  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Homer3

Human
homologs
Human Homolog HOMER3, homer homolog 3 (Drosophila)
NCBI Gene ID 9454
neXtProt AC  NX_Q9NSC5
Human Synonyms  HOMER-3, VESL3
Human Chr (Location)  19p13.11; chr19:18929201-18941258 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(16) Targeted(3)
 
Homozygous mutants exhibit normal sensitivity to cocaine.
 
Interactions
Homer3 interacts with 152 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process G-protein coupled glutamate receptor signaling pathway
Component basal part of cell, cell junction, ...
Function protein binding, protein C-terminus binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000022250 (Evidence)
Ensembl Gene ModelENSMUSG00000003573 (Evidence)
Entrez Gene26558 (Evidence)
NIA Mouse Gene IndexU101083
Consensus CDS ProjectCCDS22363.1, CCDS52569.1
International Mouse Knockout Project StatusHomer3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022250 VEGA Gene Model | MGI Sequence Detail 11535 C57BL/6J ±  kb
transcript OTTMUST00000052956 VEGA | MGI Sequence Detail 2323 Not Applicable 
polypeptide OTTMUSP00000025159 VEGA | MGI Sequence Detail 359 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(84 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000697 EVH1
InterPro IPR011993 Pleckstrin homology-like domain
Protein Ontology PR:000008680 homer protein homolog 3
References (Earliest) J:50718 Xiao B, et al., Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron. 1998 Oct;21(4):707-16
(Latest) J:200071 Park JM, et al., A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization. Cell. 2013 Aug 1;154(3):637-50
All references(45)
Other
accession IDs
MGI:2142770

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory