Pnck
Gene Detail

Symbol Name ID

Pnck pregnancy upregulated non-ubiquitously expressed CaM kinase MGI:1347357

Synonyms

Bstk3, Camk1b, CaMKIbeta2, Punc

Feature Type

protein coding gene

Genetic Map

Chromosome X

37.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

ChrX:73655994-73660117 bp, - strand From VEGA annotation of GRCm38   4124 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:128728  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Pnck

Human homologs

Human Homolog		PNCK, pregnancy up-regulated non-ubiquitously expressed CaM kinase
NCBI Gene ID		139728
neXtProt AC		NX_Q6P2M8
Human Synonyms		BSTK3, CaMK1b
Human Chr (Location)		Xq28; chrX:152935188-152939816 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	phosphorylation
Component	calcium- and calmodulin-dependent protein kinase complex, cytoplasm, ...
Function	ATP binding, calmodulin binding, ...

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (164)    Tissues (95)    Images (19)
Theiler Stages: 22, 26, 28

Assay Type	Results
RNA in situ	163
RT-PCR	1

cDNA source data(25)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(27) cDNA(25) Primer pair(2)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000017681 (Evidence)
Ensembl Gene Model	ENSMUSG00000002012 (Evidence)
Entrez Gene	93843 (Evidence)
UniGene	89564
DFCI	TC1582285, TC1652462
DoTS	DT.101357086, DT.111033797, DT.524713
NIA Mouse Gene Index	U039455
EC	2.7.11.17
Consensus CDS Project	CCDS30207.1
International Mouse Knockout Project Status	Pnck

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017681	VEGA Gene Model | MGI Sequence Detail	4124	C57BL/6J
transcript	OTTMUST00000043442	VEGA | MGI Sequence Detail	1492	Not Applicable
polypeptide	OTTMUSP00000019516	VEGA | MGI Sequence Detail	343	Not Applicable

All sequences(46) RefSeq(6) UniProt(4)

Polymorphisms

RFLP(1) : SNPs(3 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR020636	Calcium/calmodulin-dependent/calcium-dependent protein kinase
InterPro	IPR017441	Protein kinase, ATP binding site
InterPro	IPR000719	Protein kinase, catalytic domain
InterPro	IPR011009	Protein kinase-like domain
InterPro	IPR002290	Serine/threonine- / dual-specificity protein kinase, catalytic domain
InterPro	IPR008271	Serine/threonine-protein kinase, active site
Protein Ontology	PR:000012923	calcium/calmodulin-dependent protein kinase type 1B

References

(Earliest) J:44157 Chodosh LA, et al., Mammary gland development, reproductive history, and breast cancer risk. Cancer Res. 1999 Apr 1;59(7 Suppl):1765-1771s; discussion 1771s-1
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Other accession IDs

MGI:1349655