Atp2b3
Gene Detail

Symbol Name ID

Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 MGI:1347353

Synonyms

6430519O13Rik, Pmca3

Feature Type

protein coding gene

Genetic Map

Chromosome X

37.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

ChrX:73503086-73571005 bp, + strand From VEGA annotation of GRCm38   67920 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:123775  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: Na(+)/K(+)-transporting ATPase alpha chain
Gene Tree: Atp2b3

Human homologs

Human Homolog		ATP2B3, ATPase, Ca++ transporting, plasma membrane 3
NCBI Gene ID		492
neXtProt AC		NX_Q16720
Human Synonyms		PMCA3, PMCA3a, SCAX1
Human Chr (Location)		Xq28; chrX:152801580-152848387 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ATP2B3

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Component	integral to membrane, membrane, ...
Function	ATP binding, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (99)    Tissues (95)    Images (14)
Theiler Stages: 15, 22

Assay Type	Results
RNA in situ	94
Western blot	5

cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(9) cDNA(9)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000017670 (Evidence)
Ensembl Gene Model	ENSMUSG00000031376 (Evidence)
Entrez Gene	320707 (Evidence)
UniGene	210095
DFCI	TC1586624, TC1607037, TC1688118
DoTS	DT.111038900, DT.55280526, DT.91356825, DT.91376256
NIA Mouse Gene Index	U019938
Consensus CDS Project	CCDS30205.1
International Mouse Knockout Project Status	Atp2b3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017670	VEGA Gene Model | MGI Sequence Detail	67920	C57BL/6J
transcript	OTTMUST00000042868	VEGA | MGI Sequence Detail	4483	Not Applicable
polypeptide	OTTMUSP00000019255	VEGA | MGI Sequence Detail	1220	Not Applicable

All sequences(36) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(201 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023306	ATPase, cation-transporting, domain N
InterPro	IPR008250	ATPase, P-type, ATPase-associated domain
InterPro	IPR006408	ATPase, P-type, calcium-transporting, PMCA-type
InterPro	IPR006068	ATPase, P-type cation-transporter, C-terminal
InterPro	IPR004014	ATPase, P-type cation-transporter, N-terminal
InterPro	IPR023299	ATPase, P-type, cytoplasmic domain N
InterPro	IPR023300	ATPase, P-type, cytoplasmic transduction domain A
InterPro	IPR001757	ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter
InterPro	IPR018303	ATPase, P-type phosphorylation site
InterPro	IPR023298	ATPase, P-type, transmembrane domain
InterPro	IPR023214	HAD-like domain
InterPro	IPR005834	Haloacid dehalogenase-like hydrolase
InterPro	IPR022141	Plasma membrane calcium transporter ATPase C-terminal
Protein Ontology	PR:000004447	plasma membrane calcium-transporting ATPase 3

References

(Earliest) J:57237 Zacharias DA, et al., Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse. Biochim Biophys Acta. 1999 Aug 5;1428(2-3):397-405
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Other accession IDs

MGI:2444577