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Atp2b3 Gene Detail
Summary
  • Symbol
    Atp2b3
  • Name
    ATPase, Ca++ transporting, plasma membrane 3
  • Synonyms
    6430519O13Rik, Pmca3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347353
    NCBI Gene: 320707
  • Gene Overview
    MyGene.info: ATP2B3
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:73503086-73571005 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    206 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347353
protein coding gene ChrX:73503023-73573275 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035812
protein coding gene ChrX:69255782-69328281 (+)
A/J MGP_AJ_G0035793
protein coding gene ChrX:69469993-69537553 (+)
AKR/J MGP_AKRJ_G0035718
protein coding gene ChrX:71277526-71344941 (+)
BALB/cJ MGP_BALBcJ_G0035778
protein coding gene ChrX:68501726-68570242 (+)
C3H/HeJ MGP_C3HHeJ_G0035483
protein coding gene ChrX:69738191-69807030 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036308
protein coding gene ChrX:71391444-71465583 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033152
protein coding gene ChrX:68508854-68576547 (+)
CAST/EiJ MGP_CASTEiJ_G0034774
protein coding gene ChrX:55083190-55153140 (+)
CBA/J MGP_CBAJ_G0035458
protein coding gene ChrX:73336835-73415126 (+)
DBA/2J MGP_DBA2J_G0035615
protein coding gene ChrX:68933859-69001520 (+)
FVB/NJ MGP_FVBNJ_G0035559
protein coding gene ChrX:68260495-68328953 (+)
LP/J MGP_LPJ_G0035700
protein coding gene ChrX:70055251-70123201 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035597
protein coding gene ChrX:75931128-76001146 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036330
protein coding gene ChrX:69090426-69158043 (+)
PWK/PhJ MGP_PWKPhJ_G0034473
protein coding gene ChrX:53103206-53172796 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034307
protein coding gene ChrX:56000282-56069203 (+)
WSB/EiJ MGP_WSBEiJ_G0034915
protein coding gene ChrX:68361272-68430162 (+)



Homology
more
  • Human Ortholog
    ATP2B3, ATPase plasma membrane Ca2+ transporting 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ATP2B3, ATPase plasma membrane Ca2+ transporting 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CFAP39, CLA2, OPCA, PMCA3, PMCA3a, SCAX1
  • Links
    NCBI Gene ID: 492
    neXtProt AC: NX_Q16720
    UniProt: Q16720

  • Chr Location
    Xq28; chrX:153517677-153582929 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031376 Ensembl Gene Model | MGI Sequence Detail 67920 C57BL/6J ±  kb
transcript ENSMUST00000088429 Ensembl | MGI Sequence Detail 4483 Not Applicable  
polypeptide ENSMUSP00000085775 Ensembl | MGI Sequence Detail 1220 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • EC
  • InterPro Domains
    IPR006068 Cation-transporting P-type ATPase, C-terminal
    IPR004014 Cation-transporting P-type ATPase, N-terminal
    IPR036412 HAD-like superfamily
    IPR023214 HAD superfamily
    IPR030325 Plasma membrane calcium-transporting ATPase 3
    IPR022141 Plasma membrane calcium transporting P-type ATPase, C-terminal
    IPR001757 P-type ATPase
    IPR008250 P-type ATPase, A domain superfamily
    IPR023299 P-type ATPase, cytoplasmic domain N
    IPR018303 P-type ATPase, phosphorylation site
    IPR006408 P-type ATPase, subfamily IIB
    IPR023298 P-type ATPase, transmembrane domain superfamily
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2444577
References
more
  • Summaries
    All 30
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:57237 Zacharias DA, et al., Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse. Biochim Biophys Acta. 1999 Aug 5;1428(2-3):397-405
  • Latest
    J:263687 Wang CX, et al., METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 2018 Jun;16(6):e2004880

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory