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Slc27a4
Gene Detail
Symbol

Name
ID
Slc27a4
solute carrier family 27 (fatty acid transporter), member 4
MGI:1347347
Synonyms
FATP4, fatty acid transport protein 4
Feature Type
protein coding gene
Genetic Map
Chromosome 2
20.64 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:29802634-29817522 bp, + strand
From VEGA annotation of GRCm38

  14889 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68437  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc27a4

Human
homologs
Human Homolog SLC27A4, solute carrier family 27 (fatty acid transporter), member 4
NCBI Gene ID 10999
neXtProt AC  NX_Q6P1M0
Human Synonyms  ACSVL4, FATP4, IPS
Human Chr (Location)  9q34.11; chr9:128340560-128361470 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SLC27A4
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(2) Spontaneous(2) Targeted(9)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice are not viable. While mice of one mutant line die during early development, mice of other mutant lines die at birth exhibiting abnormal skin.
 
Human Diseases Modeled Using Mouse Slc27a4 (2)    Alleles Annotated to Human Diseases(3)    Phenotype Images(10)
Interactions
Slc27a4 interacts with 220 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (11 records)
Data Summary: Results (102)    Tissues (102)    Images (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
Northern blot 8
cDNA source data(73)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(75) Genomic(1) cDNA(73) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000012688 (Evidence)
Ensembl Gene ModelENSMUSG00000059316 (Evidence)
Entrez Gene26569 (Evidence)
UniGene330113
DFCITC1576419
DoTSDT.530666
NIA Mouse Gene IndexU001562
EC6.2.1.-
Consensus CDS ProjectCCDS15858.1
International Mouse Knockout Project StatusSlc27a4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012688 VEGA Gene Model | MGI Sequence Detail 14889 C57BL/6J ±  kb
transcript OTTMUST00000030248 VEGA | MGI Sequence Detail 4054 Not Applicable 
polypeptide OTTMUSP00000013611 VEGA | MGI Sequence Detail 643 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020845 AMP-binding, conserved site
InterPro IPR000873 AMP-dependent synthetase/ligase
InterPro IPR025110 Domain of unknown function DUF4009
InterPro IPR022272 Lipocalin conserved site
Protein Ontology PR:000015048 long-chain fatty acid transport protein 4
References
(Earliest) J:42634 Hirsch D, et al., A family of fatty acid transporters conserved from mycobacterium to man. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8625-9
(Latest) J:201436 Chang I, et al., Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice. J Clin Invest. 2013 Jun 3;123(6):2643-53
All references(62)
Disease annotation references (3)
Other
accession IDs
MGI:2139436

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory