About   Help   FAQ
Ceacam2
Gene Detail
 Symbol
Name
ID
Member of
Ceacam2
carcinoembryonic antigen-related cell adhesion molecule 2
MGI:1347246
Cea cluster
Synonyms Bgp2
Feature Type protein coding gene
Genetic Map
Chromosome 7
13.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:25516042-25539857 bp, - strand
From VEGA annotation of GRCm38

  23816 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128630  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 4 dog

Gene Tree: Ceacam2

Human
homologs
Human Homolog CEACAM1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
NCBI Gene ID 634
neXtProt AC  NX_P13688
Human Synonyms  BGP, BGP1, BGPI
Human Chr (Location)  19q13.2; chr19:42507306-42528509 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit female-specific obesity, disruption in glucose homeostasis, hyperphagia, hyperinsulinemia and decreased energy expenditure.
 
Interactions
Ceacam2 interacts with 284 markers (Mir10a, Mir10b, Mir16-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process negative regulation of brown fat cell proliferation, negative regulation of feeding behavior, ...
Component cell surface, external side of plasma membrane, ...
Function protein homodimerization activity, protein kinase binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (20)    Tissues (20)   
Theiler Stages: 13, 15, 20, 26, 28
Assay TypeResults
RT-PCR 20
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) Genomic(3) cDNA(3) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000025351 (Evidence)
Ensembl Gene ModelENSMUSG00000054385 (Evidence)
Entrez Gene26367 (Evidence)
NIA Mouse Gene IndexU361387
Consensus CDS ProjectCCDS20986.1, CCDS52152.1, CCDS52153.1
International Mouse Knockout Project StatusCeacam2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025351 VEGA Gene Model | MGI Sequence Detail 23816 C57BL/6J ±  kb
transcript OTTMUST00000062402 VEGA | MGI Sequence Detail 3140 Not Applicable 
polypeptide OTTMUSP00000030752 VEGA | MGI Sequence Detail 340 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(230 from dbSNP Build 137)    SNPs within 2kb including multiple locations(368)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000006178 carcinoembryonic antigen-related cell adhesion molecule 2
References (Earliest) J:18755 Nedellec P, et al., Bgp2, a new member of the carcinoembryonic antigen-related gene family, encodes an alternative receptor for mouse hepatitis viruses. J Virol. 1994 Jul;68(7):4525-37
(Latest) J:190991 Salaheldeen E, et al., Molecular cloning and localization of a CEACAM2 isoform, CEACAM2-L, expressed in spermatids in mouse testis. Mol Reprod Dev. 2012 Dec;79(12):843-52
All references(26)
Other
accession IDs
MGD-MRK-16441, MGI:2141896, MGI:99656

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/23/2014
MGI 5.19
The Jackson Laboratory