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Ceacam1 Gene Detail
Summary
  • Symbol
    Ceacam1
  • Name
    carcinoembryonic antigen-related cell adhesion molecule 1
  • Synonyms
    Bgp, Bgp1, Cc1, C-CAM, CD66a, Cea1, Cea-1, Cea7, Cea-7, Hv2, Hv-2, mCEA1, Mhv-1, MHVR1, mmCGM1, mmCGM2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347245
    NCBI Gene: 26365
  • Member of
    Cea cluster
  • Gene Overview
    MyGene.info: CEACAM1
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:25461707-25477603 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 13.84 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    130 from dbSNP Build 142
  • Strain Annotations
    15
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347245
protein coding gene Chr7:25461702-25477625 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031867
protein coding gene Chr7:23943257-23961911 (-)
A/J MGP_AJ_G0031847
protein coding gene Chr7:23311295-23342658 (-)
AKR/J MGP_AKRJ_G0031776
protein coding gene Chr7:23888300-24018047 (-)
BALB/cJ MGP_BALBcJ_G0031829
protein coding gene Chr7:22869640-23638053 (-)
C3H/HeJ MGP_C3HHeJ_G0031572
protein coding gene Chr7:24300234-24363738 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032315
protein coding gene Chr7:24751019-24830798 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029370
protein coding gene Chr7:24730059-24745891 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031537
protein coding gene Chr7:25656625-25676147 (-)
DBA/2J MGP_DBA2J_G0031691
protein coding gene Chr7:23221854-23308836 (-)
FVB/NJ MGP_FVBNJ_G0031644
protein coding gene Chr7:23228753-23334149 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0031682
protein coding gene Chr7:25353620-25434341 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032347
protein coding gene Chr7:23575706-23659996 (-)
PWK/PhJ MGP_PWKPhJ_G0030636
protein coding gene Chr7:18118769-18254827 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0031015
protein coding gene Chr7:23762454-23805897 (-)



Homology
more
  • Human Ortholog
    CEACAM1, carcinoembryonic antigen related cell adhesion molecule 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CEACAM1, carcinoembryonic antigen related cell adhesion molecule 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BGP, BGP1, BGPI
  • Links
    NCBI Gene ID: 634
    neXtProt AC: NX_P13688
    UniProt: P13688

  • Chr Location
    19q13.2; chr19:42507306-42528509 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 8 alleles in 8 genetic backgrounds
    1 phenotype from multigenic genotypes
    46 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice lacking appreciable levels of the two isoforms containing 4 Ig domains and having increased levels of the two isoforms containing 2 Ig domains are viable and fertile. They are significantly more resistant to mouse hepatitis virus than wild-type mice.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000074272 Ensembl Gene Model | MGI Sequence Detail 15897 C57BL/6J ±  kb
    transcript ENSMUST00000098669 Ensembl | MGI Sequence Detail 2873 Not Applicable  
    polypeptide ENSMUSP00000096266 Ensembl | MGI Sequence Detail 521 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 44
      Genomic 7
      cDNA 32
      Primer pair 3
      Other 2

      Microarray probesets 12
    Other
    Accession IDs
    less
    MGD-MRK-11017, MGD-MRK-11019, MGD-MRK-12228, MGD-MRK-1555, MGD-MRK-16442, MGD-MRK-1902, MGD-MRK-1908, MGD-MRK-1909, MGD-MRK-1915, MGI:88366, MGI:88372, MGI:96289, MGI:99657
    References
    more
    • Summaries
      All 119
      Developmental Gene Expression 11
      Gene Ontology 35
      Phenotypes 46
    • Earliest
      J:6541 Knobler RL, et al., Mouse hepatitis virus type 4 (JHM strains). induced fatal central nervous system disease. I. genetic control and murine neuron as the susceptible site of disease. J Exp Med. 1981 Apr 1;153(4):832-43
    • Latest
      J:240703 Peng G, et al., Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor. J Biol Chem. 2017 Feb 10;292(6):2174-2181

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory