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Slc27a5
Gene Detail
 Symbol
Name
ID
Slc27a5
solute carrier family 27 (fatty acid transporter), member 5
MGI:1347100
Synonyms FACVL3, FATP5, VLCSH2, VLCS-H2
Feature Type protein coding gene
Genetic Map
Chromosome 7
7.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:12988346-12998192 bp, - strand
From VEGA annotation of GRCm38

  9847 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7596  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Gene Tree: Slc27a5

Human
homologs
Human Homolog SLC27A5, solute carrier family 27 (fatty acid transporter), member 5
NCBI Gene ID 10998
neXtProt AC  NX_Q9Y2P5
Human Synonyms  ACSB, ACSVL6, BACS, BAL, FACVL3, FATP5, FATP-5, VLACSR, VLCSH2, VLCS-H2
Human Chr (Location)  19q13.43; chr19:58498333-58512065 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a null allele exhibit altered lipid homeostasis.
 
Interactions
Slc27a5 interacts with 47 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process bile acid biosynthetic process, bile acid metabolic process, ...
Component basal plasma membrane, endoplasmic reticulum, ...
Function ATP binding, catalytic activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (124)    Tissues (124)    Images (2)
Theiler Stages: 22, 28
Assay TypeResults
RNA in situ 116
Northern blot 8
cDNA source data(104)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(105) cDNA(104) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027130 (Evidence)
Ensembl Gene ModelENSMUSG00000030382 (Evidence)
Entrez Gene26459 (Evidence)
UniGene10984
DFCITC1577087
DoTSDT.535522, DT.94255704
NIA Mouse Gene IndexU088245
EC6.2.1.7
Consensus CDS ProjectCCDS20821.1
International Mouse Knockout Project StatusSlc27a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027130 VEGA Gene Model | MGI Sequence Detail 9847 C57BL/6J ±  kb
transcript OTTMUST00000067107 VEGA | MGI Sequence Detail 2288 Not Applicable 
polypeptide OTTMUSP00000033716 VEGA | MGI Sequence Detail 689 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(2) UniProt(5)
Polymorphisms SNPs within 2kb(96 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020845 AMP-binding, conserved site
InterPro IPR000873 AMP-dependent synthetase/ligase
InterPro IPR025110 Domain of unknown function DUF4009
Protein Ontology PR:000015049 bile acyl-CoA synthetase
References (Earliest) J:42634 Hirsch D, et al., A family of fatty acid transporters conserved from mycobacterium to man. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8625-9
(Latest) J:178094 Mishima T, et al., The expression and function of fatty acid transport protein-2 and -4 in the murine placenta. PLoS One. 2011;6(10):e25865
All references(38)
Other
accession IDs
MGI:1313298

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory