Slc27a2
Gene Detail

Symbol Name ID

Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 MGI:1347099

Synonyms

ACSVL1, FATP2, FATP2, Vlac, Vlacs, VLCS

Feature Type

protein coding gene

Genetic Map

Chromosome 2

61.76 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:126552407-126588243 bp, + strand From VEGA annotation of GRCm38   35837 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37830  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Slc27a2

Human homologs

Human Homolog		SLC27A2, solute carrier family 27 (fatty acid transporter), member 2
NCBI Gene ID		11001
neXtProt AC		NX_O14975
Human Synonyms		ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS
Human Chr (Location)		15q21.2; chr15:50474393-50528589 (+)  GRCh37.p13

Alleles and phenotypes

All alleles(5) : Targeted(4) Gene trapped(1)
 

Homozygous mutant mice are viable and show no gross morphological abnormalities.

 

Gene Ontology (GO) classifications

All GO classifications: (51 annotations)

Process	bile acid biosynthetic process, fatty acid alpha-oxidation, ...
Component	endoplasmic reticulum, endoplasmic reticulum lumen, ...
Function	ATP binding, catalytic activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (12 records)

Data Summary: Results (357)    Tissues (256)    Images (34)
Theiler Stages: 17, 20, 21, 22, 23, 26, 28

Assay Type	Results
RNA in situ	320
Northern blot	27
RT-PCR	10

cDNA source data(173)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(176) cDNA(173) Primer pair(3)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000015755 (Evidence)
Ensembl Gene Model	ENSMUSG00000027359 (Evidence)
Entrez Gene	26458 (Evidence)
UniGene	290044
DFCI	TC1572822, TC1630418
DoTS	DT.101706333, DT.533597
NIA Mouse Gene Index	U002419, U023302
EC	6.2.1.-, 6.2.1.3
Consensus CDS Project	CCDS16683.1
International Mouse Knockout Project Status	Slc27a2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000015755	VEGA Gene Model | MGI Sequence Detail	35837	C57BL/6J
transcript	OTTMUST00000037419	VEGA | MGI Sequence Detail	2918	Not Applicable
polypeptide	OTTMUSP00000016767	VEGA | MGI Sequence Detail	620	Not Applicable

All sequences(38) RefSeq(2) UniProt(4)

Polymorphisms

SNPs within 2kb(342 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR020845	AMP-binding, conserved site
InterPro	IPR000873	AMP-dependent synthetase/ligase
InterPro	IPR025110	Domain of unknown function DUF4009
Protein Ontology	PR:000015046	very long-chain acyl-CoA synthetase

References

(Earliest) J:42534 Pirard M, et al., Comparison of PMM1 with the phosphomannomutases expressed in rat liver and in human cells. FEBS Lett. 1997 Jul 14;411(2-3):251-4
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(50)

Other accession IDs

MGI:1330825