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Slc27a2
Gene Detail
 Symbol
Name
ID
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
MGI:1347099
Synonyms ACSVL1, FATP2, FATP2, Vlac, Vlacs, VLCS
Feature Type protein coding gene
Genetic Map
Chromosome 2
61.76 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:126552407-126588243 bp, + strand
From VEGA annotation of GRCm38

  35837 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37830  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Slc27a2

Human
homologs
Human Homolog SLC27A2, solute carrier family 27 (fatty acid transporter), member 2
NCBI Gene ID 11001
neXtProt AC  NX_O14975
Human Synonyms  ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS
Human Chr (Location)  15q21.2; chr15:50182196-50236392 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice are viable and show no gross morphological abnormalities.
 
Interactions
Slc27a2 interacts with 50 markers (Mir19a, Mir125a, Mir143, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (76 annotations)
Process bile acid biosynthetic process, fatty acid alpha-oxidation, ...
Component endoplasmic reticulum, endoplasmic reticulum lumen, ...
Function 2,4,4-trimethylpentanoate-CoA ligase activity, 2,4-dichlorobenzoate-CoA ligase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (357)    Tissues (256)    Images (34)
Theiler Stages: 17, 20, 21, 22, 23, 26, 28
Assay TypeResults
RNA in situ 320
Northern blot 27
RT-PCR 10
cDNA source data(173)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(176) cDNA(173) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000015755 (Evidence)
Ensembl Gene ModelENSMUSG00000027359 (Evidence)
Entrez Gene26458 (Evidence)
UniGene290044
DFCITC1572822, TC1630418
DoTSDT.101706333, DT.533597
NIA Mouse Gene IndexU002419, U023302
EC6.2.1.-, 6.2.1.3
Consensus CDS ProjectCCDS16683.1
International Mouse Knockout Project StatusSlc27a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015755 VEGA Gene Model | MGI Sequence Detail 35837 C57BL/6J ±  kb
transcript OTTMUST00000037419 VEGA | MGI Sequence Detail 2918 Not Applicable 
polypeptide OTTMUSP00000016767 VEGA | MGI Sequence Detail 620 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(342 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020845 AMP-binding, conserved site
InterPro IPR000873 AMP-dependent synthetase/ligase
InterPro IPR025110 Domain of unknown function DUF4009
Protein Ontology PR:000015046 very long-chain acyl-CoA synthetase
References (Earliest) J:42534 Pirard M, et al., Comparison of PMM1 with the phosphomannomutases expressed in rat liver and in human cells. FEBS Lett. 1997 Jul 14;411(2-3):251-4
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(52)
Other
accession IDs
MGI:1330825

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory