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Slc27a1
Gene Detail
Symbol

Name
ID
Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
MGI:1347098
Synonyms
Fatp, FATP1
Feature Type
protein coding gene
Genetic Map
Chromosome 8
34.43 cM, cytoband B3.3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:71568927-71586708 bp, + strand
From Ensembl annotation of GRCm38

  17782 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8063  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

HCOP human homology predictions: SLC27A1
Gene Tree: Slc27a1

Human
homologs
SLC27A1, solute carrier family 27 (fatty acid transporter), member 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 376497
neXtProt AC: NX_Q6PCB7

Human Synonyms: ACSVL5, FATP, FATP1, FATP-1

Human Chr (Location): 19p13.11; chr19:17468774-17506168 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous null mutants are protected from fat-induced insulin resistance and intramuscular accumulation of fatty acid metabolites without alterations in whole body adiposity.
 
Interactions
Slc27a1 interacts with 97 markers (Mir1b, Mir7-1, Mir15a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (8 records)
Data Summary: Results (501)    Tissues (155)    Images (63)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 493
Northern blot 8
cDNA source data(61)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN slc27a1a    NEW 
Molecular
reagents
All nucleic(65) Genomic(3) cDNA(61) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000031808 (Evidence)
Entrez Gene 26457 (Evidence)
UniGene 38165
DFCI TC1582895, TC1683235
DoTS DT.101353173, DT.101249717, DT.87055192, DT.110867865, DT.526863
NIA Mouse Gene Index U042913
EC 6.2.1.-
Consensus CDS Project CCDS40386.1
International Mouse Phenotyping Consortium Status Slc27a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031808 Ensembl Gene Model | MGI Sequence Detail 17782 C57BL/6J ±  kb
transcript ENSMUST00000034267 Ensembl | MGI Sequence Detail 2795 Not Applicable 
polypeptide ENSMUSP00000034267 Ensembl | MGI Sequence Detail 646 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(19) UniProt(4)
Polymorphisms
SNPs within 2kb(156 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020845 AMP-binding, conserved site
InterPro IPR000873 AMP-dependent synthetase/ligase
InterPro IPR025110 Domain of unknown function DUF4009
Protein Ontology PR:000015045 long-chain fatty acid transport protein 1
References
(Earliest) J:21397 Schaffer JE, et al., Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein [see comments]. Cell. 1994 Nov 4;79(3):427-36
(Latest) J:217937 Lin MH, et al., Fatty Acid transport protein 1 can compensate for Fatty Acid transport protein 4 in the developing mouse epidermis. J Invest Dermatol. 2015 Feb;135(2):462-70
All references(52)
Other
accession IDs
MGD-MRK-19704, MGI:102796

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory