Cd97
Gene Detail

Symbol Name ID

Cd97 CD97 antigen MGI:1347095

Synonyms

EGF-TM7 receptor

Feature Type

protein coding gene

Genetic Map

Chromosome 8

40.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr8:83723251-83741326 bp, - strand From VEGA annotation of GRCm38   18076 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Cd97 ± 2 cM)

Protein SuperFamily: EGF-like module-containing mucin-like hormone receptor-like 2 and CD97
Gene Tree: Cd97

Human ortholog

CD97 CD97 molecule NCBI Gene ID 976
Human Synonyms: TM7LN1
Human Chr19:14492213-14519535 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(55) : Targeted(6) Gene trapped(49)
 

Mice homozygous for disruptions in this gene display a normal phenotype apart from mild granulocytosis.

 

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	cell adhesion, cell surface receptor signaling pathway, ...
Component	integral to membrane, membrane, ...
Function	calcium ion binding, G-protein coupled receptor activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (260)    Tissues (121)    Images (122)
Theiler Stages: 23, 28

Assay Type	Results
RNA in situ	99
In situ reporter (knock in)	123
RT-PCR	38

cDNA source data(92)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(94) cDNA(93) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000022225 (Evidence)
Ensembl Gene Model	ENSMUSG00000002885 (Evidence)
Entrez Gene	26364 (Evidence)
UniGene	334648
DFCI	TC1576516, TC1588051, TC1611445, TC1661489
NIA Mouse Gene Index	U030019
Consensus CDS Project	CCDS22461.1, CCDS52610.1, CCDS52611.1, CCDS52612.1
International Mouse Knockout Project Status	Cd97

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022225	VEGA Gene Model | MGI Sequence Detail	18076	C57BL/6J
transcript	OTTMUST00000052855	VEGA | MGI Sequence Detail	3000	Not Applicable
polypeptide	OTTMUSP00000025113	VEGA | MGI Sequence Detail	818	Not Applicable

All sequences(60) RefSeq(8) UniProt(5)

Polymorphisms

RFLP(1) : SNPs(87 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001881	EGF-like calcium-binding
InterPro	IPR018097	EGF-like calcium-binding, conserved site
InterPro	IPR000152	EGF-type aspartate/asparagine hydroxylation site
InterPro	IPR000742	Epidermal growth factor-like domain
InterPro	IPR003056	GPCR, family 2, CD97 antigen
InterPro	IPR017981	GPCR, family 2-like
InterPro	IPR000832	GPCR, family 2, secretin-like
InterPro	IPR000203	GPS domain
Protein Ontology	PR:000001311	CD97 molecule

References

(Earliest) J:57794 Carver EA, et al., Physical mapping of EMR1 and CD97 in human Chromosome 19 and assignment of Cd97 to mouse Chromosome 8 suggest an ancient genomic duplication. Mamm Genome. 1999 Oct;10(10):1039-40
(Latest) J:178122 Veninga H, et al., A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense. PLoS One. 2011;6(10):e24431
All references(39)

Other accession IDs

MGI:2142420