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Creb3l1
Gene Detail
Symbol

Name
ID
Creb3l1
cAMP responsive element binding protein 3-like 1
MGI:1347062
Synonyms
BBF-2 (drosophila) homolog, MGC:25246, Oasis
Feature Type
protein coding gene
Genetic Map
Chromosome 2
50.63 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:91982328-92024502 bp, - strand
From VEGA annotation of GRCm38

  42175 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8058  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CREB3L1
Gene Tree: Creb3l1

Human
homologs
CREB3L1, cAMP responsive element binding protein 3-like 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 90993
neXtProt AC: NX_Q96BA8

Human Synonyms: OASIS

Human Chr (Location): 11p11.2; chr11:46277638-46321422 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(21) Targeted(5)
Genomic Mutations involving Creb3l1 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit postnatal growth retardation, fragile skeleton, and decreased bone density, cortical and trabecular thickness, and osteoblast maturation.
 
Interactions
Creb3l1 interacts with 155 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (14 records)
Data Summary: Results (186)    Tissues (75)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 186
cDNA source data(56)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase creb3l1 ; ZFIN creb3l1    NEW 
Molecular
reagents
All nucleic(57) cDNA(57)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000014377 (Evidence)
Ensembl Gene Model ENSMUSG00000027230 (Evidence)
Entrez Gene 26427 (Evidence)
UniGene 10353
DFCI TC1696875, TC1582690
DoTS DT.489103
NIA Mouse Gene Index U023031
Consensus CDS Project CCDS38181.1
International Mouse Phenotyping Consortium Status Creb3l1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014377 VEGA Gene Model | MGI Sequence Detail 42175 C57BL/6J ±  kb
transcript OTTMUST00000034017 VEGA | MGI Sequence Detail 2603 Not Applicable 
polypeptide OTTMUSP00000015236 VEGA | MGI Sequence Detail 520 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(280 from dbSNP Build 137)    SNPs within 2kb including multiple locations(284)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR001630 cAMP response element binding (CREB) protein
Protein Ontology PR:000005856 cyclic AMP-responsive element-binding protein 3-like protein 1
References
(Earliest) J:57177 Honma Y, et al., Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue. Brain Res Mol Brain Res. 1999 May 21;69(1):93-103
(Latest) J:217601 Delgado-Olguin P, et al., Ezh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature. Development. 2014 Dec;141(23):4610-7
All references(53)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory