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Creb3l1
Gene Detail
Symbol

Name
ID
Creb3l1
cAMP responsive element binding protein 3-like 1
MGI:1347062
Synonyms
BBF-2 (drosophila) homolog, MGC:25246, Oasis
Feature Type
protein coding gene
Genetic Map
Chromosome 2
50.63 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:91982328-92024502 bp, - strand
From VEGA annotation of GRCm38

  42175 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8058  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Creb3l1

Human
homologs
Human Homolog CREB3L1, cAMP responsive element binding protein 3-like 1
NCBI Gene ID 90993
neXtProt AC  NX_Q96BA8
Human Synonyms  OASIS
Human Chr (Location)  11p11.2; chr11:46277638-46321422 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(21) Targeted(5)
Genomic Mutations involving Creb3l1 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit postnatal growth retardation, fragile skeleton, and decreased bone density, cortical and trabecular thickness, and osteoblast maturation.
 
Interactions
Creb3l1 interacts with 155 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (13 records)
Data Summary: Results (186)    Tissues (75)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 186
cDNA source data(56)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(57) cDNA(57)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000014377 (Evidence)
Ensembl Gene ModelENSMUSG00000027230 (Evidence)
Entrez Gene26427 (Evidence)
UniGene10353
DFCITC1582690, TC1696875
DoTSDT.489103
NIA Mouse Gene IndexU023031
Consensus CDS ProjectCCDS38181.1
International Mouse Knockout Project StatusCreb3l1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014377 VEGA Gene Model | MGI Sequence Detail 42175 C57BL/6J ±  kb
transcript OTTMUST00000034017 VEGA | MGI Sequence Detail 2603 Not Applicable 
polypeptide OTTMUSP00000015236 VEGA | MGI Sequence Detail 520 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(280 from dbSNP Build 137)    SNPs within 2kb including multiple locations(284)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR001630 cAMP response element binding (CREB) protein
Protein Ontology PR:000005856 cyclic AMP-responsive element-binding protein 3-like protein 1
References
(Earliest) J:57177 Honma Y, et al., Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue. Brain Res Mol Brain Res. 1999 May 21;69(1):93-103
(Latest) J:205632 Saito A, et al., Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967
All references(47)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory